Atomic-level description of ubiquitin folding

Equilibrium molecular dynamics simulations, in which proteins spontaneously and repeatedly fold and unfold, have recently been used to help elucidate the mechanistic principles that underlie the folding of fast-folding proteins. The extent to which the conclusions drawn from the analysis of such pro...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2013-04, Vol.110 (15), p.5915-5920
Hauptverfasser: Piana, Stefano, Lindorff-Larsen, Kresten, Shaw, David E.
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Sprache:eng
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