Remote activation of biomolecules in deep tissues using near-infrared-to-UV upconversion nanotransducers

Controlled activation or release of biomolecules is very crucial in various biological applications. Controlling the activity of biomolecules have been attempted by various means and controlling the activity by light has gained popularity in the past decade. The major hurdle in this process is that...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-05, Vol.109 (22), p.8483-8488
Hauptverfasser:	Jayakumar, Muthu Kumara Gnanasammandhan, Idris, Niagara Muhammad, Zhang, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Cell Line, Tumor Cell Survival Cell Survival - radiation effects chemistry Comet Assay DNA DNA - chemistry DNA - genetics DNA - metabolism DNA Damage Female Fluorescence Gene expression genetics Green Fluorescent Proteins Green Fluorescent Proteins - chemistry Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Hindlimb Hindlimb - metabolism Hindlimb - radiation effects Imaging Infrared Rays instrumentation Irradiation Lasers Light metabolism methods Mice Mice, Inbred BALB C Microscopy, Confocal Microscopy, Electron, Transmission Microscopy, Fluorescence Molecules Muscle, Skeletal Muscle, Skeletal - metabolism Muscle, Skeletal - radiation effects Nanoparticles Nanoparticles - chemistry Nanoparticles - ultrastructure Nanotechnology Nanotechnology - instrumentation Nanotechnology - methods Nucleic acids Photochemical Processes Photochemical Processes - radiation effects Photochemistry Photochemistry - instrumentation Photochemistry - methods phototoxicity Plasmids radiation effects RNA, Small Interfering RNA, Small Interfering - chemistry RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Small interfering RNA Toxicity Transducers ultrastructure Ultraviolet radiation Ultraviolet Rays
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