Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7

The intracellular pathogen Mycobacterium tuberculosis (Mtb) causes tuberculosis. Enhanced intracellular survival (Eis) protein, secreted by Mtb. enhances survival of Mycobacterium smegmatis (Msm) in macrophages. Mtb Eis was shown to suppress host immune defenses by negatively modulating autophagy, i...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2012-05, Vol.109 (20), p.7729-7734
Hauptverfasser: Kim, Kyoung Hoon, An, Doo Ri, Song, Jinsu, Yoon, Ji Young, Kim, Hyoun Sook, Yoon, Hye Jin, Im, Ha Na, Kim, Jieun, Kim, Do Jin, Lee, Sang Jae, Kim, Ki-Hye, Lee, Hye-Mi, Kim, Hie-Joon, Jo, Eun-Kyeong, Lee, Jae Young, Suh, Se Won
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Sprache:eng
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