Compression and self-entanglement of single DNA molecules under uniform electric field

We experimentally study the effects of a uniform electric field on the conformation of single DNA molecules. We demonstrate that a moderate electric field (∼200 V/cm) strongly compresses isolated DNA polymer coils into isotropic globules. Insight into the nature of these compressed states is gained...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2011-09, Vol.108 (39), p.16153-16158
Hauptverfasser: Tang, Jing, Du, Ning, Doyle, Patrick S
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Sprache:eng
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