Expression levels of a filament-specific transcriptional regulator are sufficient to determine Candida albicans morphology and virulence

Candida albicans, the major human fungal pathogen, undergoes a reversible morphological transition from single yeast cells to pseudohyphal and hyphal filaments (elongated cells attached end-to-end). Because typical C. albicans infections contain a mixture of these morphologies it has, for many years...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2009-01, Vol.106 (2), p.599-604
Hauptverfasser: Carlisle, Patricia L, Banerjee, Mohua, Lazzell, Anna, Monteagudo, Carlos, López-Ribot, José L, Kadosh, David
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Sprache:eng
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