structure of CDK4/cyclin D3 has implications for models of CDK activation

Cyclin-dependent kinase 4 (CDK4)/cyclin D complexes are expressed early in the G₁ phase of the cell cycle and stimulate the expression of genes required for G₁ progression by phosphorylation of the product of the retinoblastoma gene, pRb. To elaborate the molecular pathway of CDK4 activation and sub...

Ausführliche Beschreibung