Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Aβ toxicity

Cells that have evolved to produce large quantities of secreted proteins to serve the integrated functions of complex multicellular organisms are equipped to compensate for protein misfolding. Hepatocytes and plasma cells have well developed chaperone and proteasome systems to ensure that secreted p...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-02, Vol.105 (7), p.2681-2686
Hauptverfasser:	Buxbaum, Joel N, Ye, Zhengyi, Reixach, Natàlia, Friske, Linsey, Levy, Coree, Das, Pritam, Golde, Todd, Masliah, Eliezer, Roberts, Amanda R, Bartfai, Tamas
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloids Animals Antibodies Biological Sciences Humans Mazes Mice Monomers Neurons Solar fibrils Transgenic animals
Online-Zugang:	Volltext
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