Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif

Rds3p, a component of the U2 snRNP subcomplex SF3b, is essential for pre-mRNA splicing and is extremely well conserved in all eukaryotic species. We report here the solution structure of Rds3p, which reveals an unusual knotted fold unrelated to previously known knotted proteins. Rds3p has a triangul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2008-07, Vol.105 (28), p.9621-9626
Hauptverfasser:	van Roon, Anne-Marie M, Loening, Nikolaus M, Obayashi, Eiji, Yang, Ji-Chun, Newman, Andrew J, Hernández, Helena, Nagai, Kiyoshi, Neuhaus, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Arias Biochemistry Biological Sciences Carrier Proteins - chemistry Cells Cysteine - chemistry Fingers Mass spectroscopy Molecular structure Protein Conformation Proteins Ribonucleoprotein, U2 Small Nuclear - chemistry RNA Saccharomyces cerevisiae Proteins - chemistry Small nuclear ribonucleoproteins Solutions Splicing Yeasts Zinc Zinc Fingers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!