Structural Insights into the Bactericidal Mechanism of Human Peptidoglycan Recognition Proteins

Peptidoglycan recognition proteins (PGRPs) are highly conserved pattern-recognition molecules of the innate immune system that bind bacterial peptidoglycans (PGNs), which are polymers of alternating N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) cross-linked by short peptide stems. Human P...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-05, Vol.104 (21), p.8761-8766
Hauptverfasser:	Cho, Sangwoo, Wang, Qian, Swaminathan, Chittoor P., Hesek, Dusan, Lee, Mijoon, Boons, Geert-Jan, Mobashery, Shahriar, Mariuzza, Roy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Atoms Bacteria Bacterial Proteins - chemistry Bacterial Proteins - metabolism Binding Sites Biochemistry Biological Sciences Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Cell Wall - metabolism Cell walls Crystal structure Crystallography, X-Ray Humans Hydrogen bonds Immune system Immunology Ligands Models, Molecular Molecules Monomers Peptides Peptidoglycan - chemistry Peptidoglycan - metabolism Polysaccharides Protein Binding Protein Structure, Quaternary Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!