Structural basis for the selection of glycosylated substrates by SCFFbs¹ ubiquitin ligase

The ubiquitin ligase complex SCFFbs¹, which contributes to the ubiquitination of glycoproteins, is involved in the endoplasmic reticulum-associated degradation pathway. In SCF ubiquitin ligases, a diverse array of F-box proteins confers substrate specificity. Fbs1/Fbx2, a member of the F-box protein...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2007-04, Vol.104 (14), p.5777-5781
Hauptverfasser: Mizushima, Tsunehiro, Yoshida, Yukiko, Kumanomidou, Taichi, Hasegawa, Yuko, Suzuki, Atsuo, Yamane, Takashi, Tanaka, Keiji
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Sprache:eng
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