Identification of a Domain in Yersinia Virulence Factor YadA That Is Crucial for Extracellular Matrix-Specific Cell Adhesion and Uptake

For many pathogens, cell adhesion factors are critical virulence determinants. Enteropathogenic Yersinia species express the afimbrial adhesin YadA, the prototype of a class of homotrimeric outer membrane adhesins, which mediates adherence to host cells by binding to extracellular matrix components....

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