Molecular Signatures in Childhood Acute Leukemia and Their Correlations to Expression Patterns in Normal Hematopoietic Subpopulations

Global expression profiles of a consecutive series of 121 childhood acute leukemias (87 B lineage acute lymphoblastic leukemias, 11 T cell acute lymphoblastic leukemias, and 23 acute myeloid leukemias), six normal bone marrows, and 10 normal hematopoietic subpopulations of different lineages and mat...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-12, Vol.102 (52), p.19069-19074
Hauptverfasser:	Anna Andersson, Tor Olofsson, David Lindgren, Nilsson, Björn, Cecilia Ritz, Patrik Edén, Carin Lassen, Johan Råde, Magnus Fontes, Helena Mörse, Jesper Heldrup, Mikael Behrendtz, Mitelman, Felix, Höglund, Mattias, Johansson, Bertil, Thoas Fioretos
Format:	Artikel
Sprache:	eng
Schlagworte:	B cell leukemia Basic Medicine Biological Sciences Bone Marrow - metabolism Bone Marrow Cells - cytology Cell Line Cell Lineage Cell lines Children & youth Chromosome Aberrations Chromosomes Clinical Medicine Cluster Analysis DNA, Complementary - metabolism Gene expression Gene Expression Regulation Gene Expression Regulation, Neoplastic Genes Genes, Neoplasm Hematologi Hematology Hematopoiesis Hematopoietic Stem Cells - cytology Hematopoietic System - metabolism Humans Klinisk medicin Leukemia Leukemia - genetics Leukemia - metabolism Leukemia, Myeloid, Acute - genetics Medical and Health Sciences Medical Genetics Medical research Medicin och hälsovetenskap Medicinsk genetik Medicinska och farmaceutiska grundvetenskaper Models, Genetic Myeloid cells Myeloid leukemia Myeloid-Lymphoid Leukemia Protein NATURAL SCIENCES NATURVETENSKAP Oligonucleotide Array Sequence Analysis Pediatrics Pediatrik Ploidies Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Principal Component Analysis Principal components analysis Quantitative genetics T lymphocytes Transcription Factors - chemistry
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