Uterine Wnt/β-Catenin Signaling Is Required for Implantation

Successful implantation relies on precisely orchestrated and reciprocal signaling between the implanting blastocyst and the receptive uterus. We have examined the role of the Wnt/β-catenin signaling pathway during the process of implantation and demonstrate that this pathway is activated during two...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2005-06, Vol.102 (24), p.8579-8584
Hauptverfasser:	Mohamed, Othman A., Jonnaert, Maud, Labelle-Dumais, Cassandre, Kuroda, Kazuki, Clarke, Hugh J., Dufort, Daniel, Roberts, R. Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta Catenin beta-Galactosidase - metabolism Biological Sciences Biology Blastocyst Cells Cytoskeletal Proteins - metabolism Embryo implantation Embryo Implantation - physiology Embryo, Mammalian - metabolism Embryos Epithelium Epithelium - metabolism Estrogens Estrogens - metabolism Female Female animals Gene Expression Regulation, Developmental Intercellular Signaling Peptides and Proteins - metabolism L cells Mice Mice, Transgenic Pregnancy Reproduction Signal transduction Signal Transduction - physiology Trans-Activators - metabolism Transgenic animals Uterus Uterus - metabolism Uterus - physiology Wnt Proteins
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