Reciprocal Relationships between Fgf8 and Neural Crest Cells in Facial and Forebrain Development

Fgf8 exerts a strong effect on the mesenchymal cells of neural crest (NC) origin that are fated to form the facial skeleton. Surgical extirpation of facial skeletogenic NC domain (including mid-diencephalon down through rhombomere 2), which does not express Hox genes, results in the failure of facia...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2004-04, Vol.101 (14), p.4843-4847
Hauptverfasser:	Creuzet, Sophie, Schuler, Bernadette, Couly, Gérard, Le Douarin, Nicole M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Sciences Biology Bones Cartilage Chick Embryo Ectoderm Embryos Face Face - embryology Fibroblast Growth Factor 8 Fibroblast Growth Factors Fibroblast Growth Factors - genetics Forebrain Gene expression In Situ Hybridization Jaw Life Sciences Nervous System Nervous System - embryology Neural crest Neurons Prenatal development Prosencephalon Prosencephalon - embryology Quail Quail - embryology Quails Signal transduction Skeletal system Skeleton
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