Efficacy of videoconferencing-delivered cognitive behavioural therapy to reduce anxiety disorder severity in LGBTQ+ people: An exploratory trial protocol
Cognitive behavior therapy (CBT) is a well-established treatment for anxiety disorders in the general population. However, the efficacy of CBT for lesbian, gay, bisexual, transgender, queer, questioning, and otherwise non-heterosexual or non-cisgender (LGBTQ+) people with anxiety disorders is still...
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| creator | Dunn, Isaac B J M D Power, Emma Casey, Liam J Wootton, Bethany M |
| description | Cognitive behavior therapy (CBT) is a well-established treatment for anxiety disorders in the general population. However, the efficacy of CBT for lesbian, gay, bisexual, transgender, queer, questioning, and otherwise non-heterosexual or non-cisgender (LGBTQ+) people with anxiety disorders is still emerging in the literature. This protocol proposes an exploratory, two-group, randomized controlled trial comparing the efficacy of CBT for anxiety disorders against a waitlist control group.
The trial will recruit 52 LGBTQ+ adults with a primary anxiety disorder diagnosis. The treatment will consist of videoconferencing-delivered CBT using the Unified Protocol (UP). The treatment will be provided in eight weekly individual sessions. Following treatment completion, the waitlist control participants will receive an LGBTQ+ adapted CBT intervention delivered via videoconferencing. The control group will receive the LGBTQ+ adapted UP in weekly sessions for eight weeks. Diagnostic status and symptom severity will be assessed at baseline, post-treatment, and three-month follow-up. Post-treatment qualitative exit interviews will collect participant perspectives on treatment acceptability.
Outcome measures will be compared across groups and benchmarked with existing literature to assess efficacy and feasibility, while qualitative analysis will explore intervention acceptability.
The results are anticipated to inform best-practice remote transdiagnostic treatment of anxiety disorders in LGBTQ+ people. |
| doi_str_mv | 10.1371/journal.pone.0316857 |
| format | Article |
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The trial will recruit 52 LGBTQ+ adults with a primary anxiety disorder diagnosis. The treatment will consist of videoconferencing-delivered CBT using the Unified Protocol (UP). The treatment will be provided in eight weekly individual sessions. Following treatment completion, the waitlist control participants will receive an LGBTQ+ adapted CBT intervention delivered via videoconferencing. The control group will receive the LGBTQ+ adapted UP in weekly sessions for eight weeks. Diagnostic status and symptom severity will be assessed at baseline, post-treatment, and three-month follow-up. Post-treatment qualitative exit interviews will collect participant perspectives on treatment acceptability.
Outcome measures will be compared across groups and benchmarked with existing literature to assess efficacy and feasibility, while qualitative analysis will explore intervention acceptability.
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The trial will recruit 52 LGBTQ+ adults with a primary anxiety disorder diagnosis. The treatment will consist of videoconferencing-delivered CBT using the Unified Protocol (UP). The treatment will be provided in eight weekly individual sessions. Following treatment completion, the waitlist control participants will receive an LGBTQ+ adapted CBT intervention delivered via videoconferencing. The control group will receive the LGBTQ+ adapted UP in weekly sessions for eight weeks. Diagnostic status and symptom severity will be assessed at baseline, post-treatment, and three-month follow-up. Post-treatment qualitative exit interviews will collect participant perspectives on treatment acceptability.
Outcome measures will be compared across groups and benchmarked with existing literature to assess efficacy and feasibility, while qualitative analysis will explore intervention acceptability.
The results are anticipated to inform best-practice remote transdiagnostic treatment of anxiety disorders in LGBTQ+ people.</description><subject>Acceptability</subject><subject>Adult</subject><subject>Analysis</subject><subject>Anxiety</subject><subject>Anxiety disorders</subject><subject>Anxiety Disorders - therapy</subject><subject>Behavior therapy</subject><subject>Behavioral health care</subject><subject>Biology and Life Sciences</subject><subject>Bisexuality</subject><subject>Care and treatment</subject><subject>Clinical trials</subject><subject>Cognition & reasoning</subject><subject>Cognitive behavioral therapy</subject><subject>Cognitive Behavioral Therapy - methods</subject><subject>Cognitive therapy</subject><subject>Consent</subject><subject>Disorders</subject><subject>Effectiveness</subject><subject>Exploratory behavior</subject><subject>Female</subject><subject>Generalized anxiety disorder</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Inclusion</subject><subject>Intervention</subject><subject>Lesbians</subject><subject>LGBTQ people</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Mental disorders</subject><subject>Mental health</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Panic attacks</subject><subject>Patient outcomes</subject><subject>Prevalence studies (Epidemiology)</subject><subject>Psychological aspects</subject><subject>Qualitative analysis</subject><subject>Qualitative research</subject><subject>Sexual and Gender Minorities - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dunn, Isaac B J M D</au><au>Power, Emma</au><au>Casey, Liam J</au><au>Wootton, Bethany M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of videoconferencing-delivered cognitive behavioural therapy to reduce anxiety disorder severity in LGBTQ+ people: An exploratory trial protocol</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2025-01-24</date><risdate>2025</risdate><volume>20</volume><issue>1</issue><spage>e0316857</spage><pages>e0316857-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Cognitive behavior therapy (CBT) is a well-established treatment for anxiety disorders in the general population. However, the efficacy of CBT for lesbian, gay, bisexual, transgender, queer, questioning, and otherwise non-heterosexual or non-cisgender (LGBTQ+) people with anxiety disorders is still emerging in the literature. This protocol proposes an exploratory, two-group, randomized controlled trial comparing the efficacy of CBT for anxiety disorders against a waitlist control group.
The trial will recruit 52 LGBTQ+ adults with a primary anxiety disorder diagnosis. The treatment will consist of videoconferencing-delivered CBT using the Unified Protocol (UP). The treatment will be provided in eight weekly individual sessions. Following treatment completion, the waitlist control participants will receive an LGBTQ+ adapted CBT intervention delivered via videoconferencing. The control group will receive the LGBTQ+ adapted UP in weekly sessions for eight weeks. Diagnostic status and symptom severity will be assessed at baseline, post-treatment, and three-month follow-up. Post-treatment qualitative exit interviews will collect participant perspectives on treatment acceptability.
Outcome measures will be compared across groups and benchmarked with existing literature to assess efficacy and feasibility, while qualitative analysis will explore intervention acceptability.
The results are anticipated to inform best-practice remote transdiagnostic treatment of anxiety disorders in LGBTQ+ people.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>39854414</pmid><doi>10.1371/journal.pone.0316857</doi><tpages>e0316857</tpages><orcidid>https://orcid.org/0009-0002-8880-6596</orcidid><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Acceptability Adult Analysis Anxiety Anxiety disorders Anxiety Disorders - therapy Behavior therapy Behavioral health care Biology and Life Sciences Bisexuality Care and treatment Clinical trials Cognition & reasoning Cognitive behavioral therapy Cognitive Behavioral Therapy - methods Cognitive therapy Consent Disorders Effectiveness Exploratory behavior Female Generalized anxiety disorder Health aspects Humans Inclusion Intervention Lesbians LGBTQ people Male Medicine and Health Sciences Mental disorders Mental health Methods Middle Aged Panic attacks Patient outcomes Prevalence studies (Epidemiology) Psychological aspects Qualitative analysis Qualitative research Sexual and Gender Minorities - psychology Sexual minorities Social anxiety Social aspects Social Sciences Stigma Stress Study Protocol Substance abuse treatment Treatment Outcome Video teleconferencing Videoconferencing |
| title | Efficacy of videoconferencing-delivered cognitive behavioural therapy to reduce anxiety disorder severity in LGBTQ+ people: An exploratory trial protocol |
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