Phosphorus-independent role of FGF23 in erythropoiesis and iron homeostasis

A number of studies have reported an association between phosphorus, red blood cell (RBC) production, and iron metabolism. However, it is difficult to distinguish whether the effect of phosphorus is direct or through the actions of FGF23, and it is not clear whether phosphorus is positively or negat...

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Veröffentlicht in:	PloS one 2024-12, Vol.19 (12), p.e0315228
Hauptverfasser:	Park, Min Young, Agoro, Rafiou, Jankauskas, Stanislovas S, Le Henaff, Carole, Sitara, Despina
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anemia Animal models Animals Biology and Life Sciences Blood Bone marrow Creatinine Cytokines Diet Dietary supplements DNA Erythrocytes Erythropoiesis Erythropoiesis - drug effects Familial Hypophosphatemic Rickets - metabolism Ferritin Fibroblast growth factor 23 Fibroblast Growth Factor-23 - metabolism Fibroblast Growth Factors - blood Fibroblast Growth Factors - metabolism Flow cytometry Gene expression Granulocytes Health aspects Hematocrit Hemoglobin Homeostasis Hypophosphatemia Iron Iron - metabolism Iron deficiency Kidneys Male Medicine and Health Sciences Metabolism Mice Mice, Inbred C57BL Nutrient deficiency Osteoprogenitor cells Phosphorus Phosphorus - blood Phosphorus - metabolism Physical Sciences Properties Research and Analysis Methods Stem cells Transferrin Transferrins
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