Assessment of risk factors for virological nonsuppression following switch to dolutegravir and lamivudine, or bictegravir, emtricitabine, and tenofovir alafenamide fumarate in a real-world cohort of treatment-experienced adults living with HIV

Conflicting data exists regarding the baseline determinants of virological nonsuppression outcomes in treatment-experienced people living with human immunodeficiency virus (PWH) switching to antiretroviral treatment (ART) with bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC/FTC/TAF) or...

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Veröffentlicht in:	PloS one 2024-11, Vol.19 (11), p.e0314003
Hauptverfasser:	Lee, Shu-Yuan, Lin, Yi-Chun, Chen, Cheng-Pin, Cheng, Shu-Hsing, Chang, Shu-Ying, Ku, Shin-Yen, Cheng, Chien-Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adult AIDS Alanine - analogs & derivatives Alanine - therapeutic use Amides Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Biology and Life Sciences Bridged Bicyclo Compounds, Heterocyclic - therapeutic use Care and treatment Complications and side effects Diagnosis Drug resistance Drug Resistance, Viral - genetics Drug Substitution Emtricitabine Emtricitabine - therapeutic use Female Health risk assessment Health risks Heterocyclic Compounds, 3-Ring - therapeutic use HIV HIV (Viruses) HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - genetics Human immunodeficiency virus Humans Inhibitors Integrase inhibitors Lamivudine Lamivudine - therapeutic use Male Medicine and Health Sciences Middle Aged Mutation Non-nucleoside reverse transcriptase inhibitors Nucleoside reverse transcriptase inhibitors Nucleosides Observational studies Oxazines - therapeutic use Patient outcomes Patients Piperazines - therapeutic use Plasma Pyridones - therapeutic use Resistance factors Retrospective Studies Risk assessment Risk Factors RNA-directed DNA polymerase Survival analysis Tenofovir Tenofovir - analogs & derivatives Tenofovir - therapeutic use Viral Load - drug effects
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