Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS in hyperbilirubinemic human serum

Unconjugated bilirubin (UCB) is a byproduct of the heme group that indicates irregularities in the metabolism of several important biological molecules, such as hemoglobin. UCB is processed by hepatic UGT1A1, which catalyzes its conjugation to the metabolites bilirubin diglucuronide (BDG) and biliru...

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Veröffentlicht in:PloS one 2024-11, Vol.19 (11), p.e0313044
Hauptverfasser: Castillo-Castañeda, Stephany M, Rivera-Espinosa, Liliana, Gómez-Garduño, Josefina, Cordova-Gallardo, Jacqueline, Chávez-Pacheco, Juan Luis, Méndez-Sánchez, Nahum
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