Sodium-dependent glucose co-transport proteins (SGLTs) are not involved in human glucose taste detection

The sweet taste of saccharides, such as sucrose and glucose, and other sweeteners is known to result from activation of the TAS1R2/R3 receptor expressed in taste receptor cells (TRCs) of the taste bud. Recent reports have suggested the existence of an additional sweet taste signaling pathway for met...

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Veröffentlicht in:	PloS one 2024-11, Vol.19 (11), p.e0313128
Hauptverfasser:	Palmer, R Kyle, Nechiporenko, Anna B, Ilies, Marc A, Winnig, Marcel, Gravina, Stephen A, Tiwari, Rashmi, Prakash, Indra
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Animals Benzene Derivatives Binding sites Biology and Life Sciences Carbohydrates Cell activation CHO Cells Cricetinae Cricetulus Engineering and Technology Epithelial cells Evaluation Female Glucose Glucose - metabolism Glucose tolerance tests Glucose transport Homeostasis Human subjects Humans Hypotheses Inhibitors Male Medicine and Health Sciences Membrane potential Membrane Potentials - drug effects Membranes Phlorhizin - pharmacology Physical Sciences Potassium Protein transport Proteins Receptors Receptors, G-Protein-Coupled - metabolism Saccharides Signal transduction Social Sciences Sodium Sodium chloride Sodium-Glucose Transporter 1 - metabolism Sucrose Sweet taste Sweeteners Taste Taste - physiology Taste buds Taste Buds - drug effects Taste Buds - metabolism Taste discrimination Taste receptor neurons Taste receptors Taste thresholds Young Adult
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