Medication adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India
Understanding the factors that influence medication adherence and the multidimensional aspects of quality of life in the elderly is of paramount importance in enhancing their overall well-being. Since geriatric patients usually suffer from multiple morbidities due to their declining age, the adheren...
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description | Understanding the factors that influence medication adherence and the multidimensional aspects of quality of life in the elderly is of paramount importance in enhancing their overall well-being. Since geriatric patients usually suffer from multiple morbidities due to their declining age, the adherence towards their medications plays a very crucial role in their quality of life.
This cross-sectional study explores the intricate relationship between medication adherence and quality of life among 310 elderly patients at a single medical college and hospital. Participants completed the Morisky Medication Adherence Scale (MMAS-8) to assess medication adherence and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire, which comprises four domains (physical health, psychological health, social relationships, and environment) to evaluate quality of life. Statistical analyses, including correlations, paired t-tests, ANOVA, and Backward Multiple Linear Regression, were employed to examine the relationships and differences among variables.
The findings indicate varying levels of medication adherence among participants, with a significant proportion exhibiting medium adherence (47.1%) and highlighting the need for interventions to address challenges in medication adherence among the elderly population. Notably, gender emerged as a significant factor influencing quality of life, with males reporting higher satisfaction across all domains compared to females. Medication adherence exhibited a significant correlation with the social relationships domain (DOM3) of the WHOQOL-BREF, underlining the importance of adherence in fostering positive social interactions.
Our study revealed a significant association between medication adherence (MMAS- 8) and the quality of life (WHOQOL-BREF) among elderly patients. We also observed noteworthy gender differences in quality-of-life perceptions. It emphasizes the need for tailored interventions that consider medication adherence issues to enhance the overall quality of life among this vulnerable population. |
doi_str_mv | 10.1371/journal.pone.0302546 |
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This cross-sectional study explores the intricate relationship between medication adherence and quality of life among 310 elderly patients at a single medical college and hospital. Participants completed the Morisky Medication Adherence Scale (MMAS-8) to assess medication adherence and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire, which comprises four domains (physical health, psychological health, social relationships, and environment) to evaluate quality of life. Statistical analyses, including correlations, paired t-tests, ANOVA, and Backward Multiple Linear Regression, were employed to examine the relationships and differences among variables.
The findings indicate varying levels of medication adherence among participants, with a significant proportion exhibiting medium adherence (47.1%) and highlighting the need for interventions to address challenges in medication adherence among the elderly population. Notably, gender emerged as a significant factor influencing quality of life, with males reporting higher satisfaction across all domains compared to females. Medication adherence exhibited a significant correlation with the social relationships domain (DOM3) of the WHOQOL-BREF, underlining the importance of adherence in fostering positive social interactions.
Our study revealed a significant association between medication adherence (MMAS- 8) and the quality of life (WHOQOL-BREF) among elderly patients. We also observed noteworthy gender differences in quality-of-life perceptions. It emphasizes the need for tailored interventions that consider medication adherence issues to enhance the overall quality of life among this vulnerable population.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0302546</identifier><identifier>PMID: 39531455</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Aged ; Aged patients ; Aged, 80 and over ; Aging ; Analysis ; Biology and Life Sciences ; Care and treatment ; Chronic illnesses ; Cross-Sectional Studies ; Data collection ; Disease management ; Drugs ; Evaluation ; Female ; Gender ; Gender aspects ; Geriatrics ; Health aspects ; Hospitals ; Humans ; India ; Informed consent ; Male ; Medical history ; Medication adherence ; Medication Adherence - psychology ; Medication Adherence - statistics & numerical data ; Medicine and Health Sciences ; Middle Aged ; Older people ; Patient compliance ; Patients ; Population ; Population (statistical) ; Public health ; Quality of Life ; Questionnaires ; Research ethics ; Sex differences ; Social aspects ; Social behavior ; Social interactions ; Social Sciences ; Social support ; Standard of living ; Statistical analysis ; Surveys and Questionnaires ; Variance analysis ; Well being</subject><ispartof>PloS one, 2024-11, Vol.19 (11), p.e0302546</ispartof><rights>Copyright: © 2024 Khaiser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2024 Public Library of Science</rights><rights>2024 Khaiser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 Khaiser et al 2024 Khaiser et al</rights><rights>2024 Khaiser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c526t-201c6f810f5931450934a7c359757e5797175f322580c12588ad17a96eeedef3</cites><orcidid>0000-0002-1720-3547 ; 0000-0003-4311-8693 ; 0000-0001-5308-3477 ; 0000-0003-0874-4314</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556742/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556742/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39531455$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kabir, Md. Feroz</contributor><creatorcontrib>Khaiser, Umaima Farheen</creatorcontrib><creatorcontrib>Sultana, Rokeya</creatorcontrib><creatorcontrib>Das, Ranajit</creatorcontrib><creatorcontrib>Alzahrani, Saeed G</creatorcontrib><creatorcontrib>Saquib, Shahabe</creatorcontrib><creatorcontrib>Shamsuddin, Shaheen</creatorcontrib><creatorcontrib>Fareed, Mohammad</creatorcontrib><title>Medication adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Understanding the factors that influence medication adherence and the multidimensional aspects of quality of life in the elderly is of paramount importance in enhancing their overall well-being. Since geriatric patients usually suffer from multiple morbidities due to their declining age, the adherence towards their medications plays a very crucial role in their quality of life.
This cross-sectional study explores the intricate relationship between medication adherence and quality of life among 310 elderly patients at a single medical college and hospital. Participants completed the Morisky Medication Adherence Scale (MMAS-8) to assess medication adherence and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire, which comprises four domains (physical health, psychological health, social relationships, and environment) to evaluate quality of life. Statistical analyses, including correlations, paired t-tests, ANOVA, and Backward Multiple Linear Regression, were employed to examine the relationships and differences among variables.
The findings indicate varying levels of medication adherence among participants, with a significant proportion exhibiting medium adherence (47.1%) and highlighting the need for interventions to address challenges in medication adherence among the elderly population. Notably, gender emerged as a significant factor influencing quality of life, with males reporting higher satisfaction across all domains compared to females. Medication adherence exhibited a significant correlation with the social relationships domain (DOM3) of the WHOQOL-BREF, underlining the importance of adherence in fostering positive social interactions.
Our study revealed a significant association between medication adherence (MMAS- 8) and the quality of life (WHOQOL-BREF) among elderly patients. We also observed noteworthy gender differences in quality-of-life perceptions. 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adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India</title><author>Khaiser, Umaima Farheen ; Sultana, Rokeya ; Das, Ranajit ; Alzahrani, Saeed G ; Saquib, Shahabe ; Shamsuddin, Shaheen ; Fareed, Mohammad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-201c6f810f5931450934a7c359757e5797175f322580c12588ad17a96eeedef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Aged patients</topic><topic>Aged, 80 and over</topic><topic>Aging</topic><topic>Analysis</topic><topic>Biology and Life Sciences</topic><topic>Care and treatment</topic><topic>Chronic illnesses</topic><topic>Cross-Sectional Studies</topic><topic>Data collection</topic><topic>Disease management</topic><topic>Drugs</topic><topic>Evaluation</topic><topic>Female</topic><topic>Gender</topic><topic>Gender aspects</topic><topic>Geriatrics</topic><topic>Health aspects</topic><topic>Hospitals</topic><topic>Humans</topic><topic>India</topic><topic>Informed consent</topic><topic>Male</topic><topic>Medical history</topic><topic>Medication adherence</topic><topic>Medication Adherence - psychology</topic><topic>Medication Adherence - statistics & numerical data</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Older people</topic><topic>Patient compliance</topic><topic>Patients</topic><topic>Population</topic><topic>Population (statistical)</topic><topic>Public health</topic><topic>Quality of Life</topic><topic>Questionnaires</topic><topic>Research ethics</topic><topic>Sex differences</topic><topic>Social aspects</topic><topic>Social behavior</topic><topic>Social interactions</topic><topic>Social Sciences</topic><topic>Social support</topic><topic>Standard of living</topic><topic>Statistical analysis</topic><topic>Surveys and 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Feroz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Medication adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2024-11-12</date><risdate>2024</risdate><volume>19</volume><issue>11</issue><spage>e0302546</spage><pages>e0302546-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Understanding the factors that influence medication adherence and the multidimensional aspects of quality of life in the elderly is of paramount importance in enhancing their overall well-being. Since geriatric patients usually suffer from multiple morbidities due to their declining age, the adherence towards their medications plays a very crucial role in their quality of life.
This cross-sectional study explores the intricate relationship between medication adherence and quality of life among 310 elderly patients at a single medical college and hospital. Participants completed the Morisky Medication Adherence Scale (MMAS-8) to assess medication adherence and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) questionnaire, which comprises four domains (physical health, psychological health, social relationships, and environment) to evaluate quality of life. Statistical analyses, including correlations, paired t-tests, ANOVA, and Backward Multiple Linear Regression, were employed to examine the relationships and differences among variables.
The findings indicate varying levels of medication adherence among participants, with a significant proportion exhibiting medium adherence (47.1%) and highlighting the need for interventions to address challenges in medication adherence among the elderly population. Notably, gender emerged as a significant factor influencing quality of life, with males reporting higher satisfaction across all domains compared to females. Medication adherence exhibited a significant correlation with the social relationships domain (DOM3) of the WHOQOL-BREF, underlining the importance of adherence in fostering positive social interactions.
Our study revealed a significant association between medication adherence (MMAS- 8) and the quality of life (WHOQOL-BREF) among elderly patients. We also observed noteworthy gender differences in quality-of-life perceptions. It emphasizes the need for tailored interventions that consider medication adherence issues to enhance the overall quality of life among this vulnerable population.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>39531455</pmid><doi>10.1371/journal.pone.0302546</doi><tpages>e0302546</tpages><orcidid>https://orcid.org/0000-0002-1720-3547</orcidid><orcidid>https://orcid.org/0000-0003-4311-8693</orcidid><orcidid>https://orcid.org/0000-0001-5308-3477</orcidid><orcidid>https://orcid.org/0000-0003-0874-4314</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | Aged Aged patients Aged, 80 and over Aging Analysis Biology and Life Sciences Care and treatment Chronic illnesses Cross-Sectional Studies Data collection Disease management Drugs Evaluation Female Gender Gender aspects Geriatrics Health aspects Hospitals Humans India Informed consent Male Medical history Medication adherence Medication Adherence - psychology Medication Adherence - statistics & numerical data Medicine and Health Sciences Middle Aged Older people Patient compliance Patients Population Population (statistical) Public health Quality of Life Questionnaires Research ethics Sex differences Social aspects Social behavior Social interactions Social Sciences Social support Standard of living Statistical analysis Surveys and Questionnaires Variance analysis Well being |
title | Medication adherence and quality of life among geriatric patients: Insights from a hospital-based cross-sectional study in India |
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