Corneal nerve loss in adolescents with obesity and acanthosis nigricans

Obesity and related metabolic abnormalities in adults are associated with peripheral neuropathy. Acanthosis nigricans (AN) is associated with insulin resistance, fatty liver, hyperlipidemia and glucose intolerance, all of which are risk factors for neuropathy. The aim of this study was to investigat...

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Veröffentlicht in:	PloS one 2024-10, Vol.19 (10), p.e0309761
Hauptverfasser:	Gad, Hoda, Dauleh, Hajar, Chirayath, Shiga, Amin, Rasha, Pasha, Maheen, Elgassim, Einas, Haris, Basma, Mohamadsalih, Ghassan, Jolkka, Sari, Biglang-Awa, Roshirl, Cuatrona, Erlinda, Inso, Gina, Razon, Gerald, Hendaus, Mohamed A, Wahbeh, Farah, Sajjadi, Fatima, Al-Hashimi, Yasmeen, AlNassr, Noor, Petropoulos, Ioannis N, Ponirakis, Georgios, Hussain, Khalid, Malik, Rayaz A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Acanthosis nigricans Acanthosis Nigricans - complications Acanthosis Nigricans - pathology Adolescent Adolescents Biology and Life Sciences Body composition Body fat Body mass index Case-Control Studies Child Cholesterol Complications and side effects Confocal microscopy Cornea Cornea - innervation Cornea - pathology Corneal diseases Damage assessment Density Dextrose Diabetes Diagnosis Electronic health records Fatty liver Female Gastrointestinal surgery Glucose Glucose tolerance Health aspects High density lipoprotein Humans Hyperlipidemia Insulin resistance Liver Liver diseases Male Medical records Medicine and Health Sciences Metabolic syndrome Microscopy Nerve Fibers - pathology Nerves Obesity Obesity - complications Obesity - pathology Obesity - physiopathology Obesity in adolescence Pediatrics People and Places Peripheral neuropathy Physiological aspects Risk factors Sensitivity analysis Systemic diseases Teenagers Triglycerides Type 2 diabetes Vibration analysis Vibration perception Youth
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