The effectiveness of vitamin D supplementation in patients with end-stage knee osteoarthritis: Study protocol for a double-blinded, randomized controlled trial

Osteoarthritis (OA) knee is one of the most common chronic degenerative conditions that imposes clinical and economic burdens on individuals and societies worldwide. Previous studies showed vitamin D levels correlated positively with lean muscle mass and grip strength, implying that vitamin D supple...

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Veröffentlicht in:	PloS one 2024-10, Vol.19 (10), p.e0309610
Hauptverfasser:	Wang, Qian-Wen, Ong, Michael Tim-Yun, Man, Gene Chi-Wai, Yeung, Yi-Man, He, Xin, Choi, Ben Chi-Yin, Ng, Jonathan Patrick, Mok, Daniel Kam-Wah, Lam, Tsz-Ping, Yung, Patrick Shu-Hang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged patients Alfacalcidol Biology and Life Sciences Calcifediol Calciferol Care and treatment Cartilage Clinical trials Dietary Supplements Double-Blind Method Ethics Evaluation Exercise Female Grip strength Health aspects Hospitals Humans Informed consent Knee Male Medicine and Health Sciences Middle Aged Muscle contraction Muscle strength Muscle Strength - drug effects Older people Orthopedics Osteoarthritis Osteoarthritis, Knee - drug therapy Outpatient care facilities Pain Patient outcomes Patients Physical fitness Physical sciences Population studies Quadriceps muscle Research and Analysis Methods Sarcopenia Sarcopenia - drug therapy Sarcopenia - prevention & control Study Protocol Surgery Treatment Outcome Vitamin D Vitamin D - administration & dosage Vitamin D - therapeutic use Vitamin D Deficiency - complications Vitamin D Deficiency - drug therapy Vitamin deficiency
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