The RECONCILE study protocol: Exploiting image-based risk stratification in early prostate cancer to discriminate progressors from non-progressors (RECONCILE)

RECONCILE (ClinicalTrials.gov:NCT04340245) will identify molecular and radiomic markers associated with clinical progression and radiological progression events in a cohort of localised, newly diagnosed Gleason 3 + 4 tumours. Molecular markers will be correlated against standard of care MRI-targeted...

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Veröffentlicht in:	PloS one 2024-10, Vol.19 (10), p.e0295994
Hauptverfasser:	Marsden, Teresa, Attard, Gerhardt, Punwani, Shonit, Giganti, Francesco, Freeman, Alex, Haider, Aiman, Wingate, Anna, Williams, Norman, Syer, Tom, Pashayan, Nora, Moore, Caroline M, Emberton, Mark, Orczyk, Clement
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Biological properties Biological samples Biology and Life Sciences Biomarkers, Tumor Biopsy Cancer Development and progression Diagnosis Disease Progression Donation of organs, tissues, etc Ethical standards Heterogeneity Histology Humans Intervention Longitudinal Studies Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medical imaging Medicine and Health Sciences Middle Aged Molecular diagnostic techniques Mortality Neoplasm Grading Next-generation sequencing Observational studies Observational Studies as Topic Oncology, Experimental Population studies Prospective Studies Prostate - diagnostic imaging Prostate - pathology Prostate cancer Prostate-Specific Antigen - blood Prostatic Neoplasms - diagnosis Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - pathology Radiomics Recruitment Research and Analysis Methods Risk Assessment - methods Risk factors Semen Standard of care Study Protocol Surveillance Tissue analysis Tumor markers Tumors
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