Peptide nucleic acids can form hairpins and bind RNA-binding proteins

RNA-binding proteins (RBPs) are a major class of proteins that interact with RNAs to change their fate or function. RBPs and the ribonucleoprotein complexes they constitute are involved in many essential cellular processes. In many cases, the molecular details of RBP:RNA interactions differ between...

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Veröffentlicht in:	PloS one 2024-09, Vol.19 (9), p.e0310565
Hauptverfasser:	Zhong, Yichen, Wilkinson-White, Lorna, Zhang, Esther, Mohanty, Biswaranjan, Zhang, Belinda B, McRae, Madeline S, Luo, Rachel, Allport, Thomas A, Duff, Anthony P, Zhao, Jennifer, El-Kamand, Serene, Du Plessis, Mar-Dean, Cubeddu, Liza, Gamsjaeger, Roland, Ataide, Sandro F, Kwan, Ann H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence Analysis Antibiotics Binding proteins Binding Sites Biology and life sciences Cloning Enzymes Eukaryotes Health aspects Hydrophobicity Medicine and Health Sciences Nucleic Acid Conformation Nucleic acids Nucleotide sequence Peptide nucleic acids Peptide Nucleic Acids - chemistry Peptide Nucleic Acids - metabolism Peptides Physical Sciences Plasmids Prokaryotes Properties Protein Binding Protein folding Protein structure Proteins Research and analysis methods Ribonucleic acid RNA RNA - chemistry RNA - metabolism RNA polymerase RNA viruses RNA-binding protein RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism SARS-CoV-2 - metabolism Severe acute respiratory syndrome coronavirus 2 Signal recognition particle Signal Recognition Particle - chemistry Signal Recognition Particle - metabolism Therapeutic targets Viral diseases
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