KNUST aging and human immunodeficiency virus outcomes-Study protocol
Globally, 7 million people with HIV (PWH) aged over 50 years exist. 5 million of them live in sub-Saharan Africa, the epicenter of the HIV epidemic. In Ghana, every 1 in 6 PWH is aged over 50 years. However, access to geriatric health care is grossly limited in Ghana and the sub-Saharan Africa regio...
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| creator | Werekuu, Alex Ayisi-Boateng, Nana Kwame Tagoe, Nadia Opoku, Douglas Aninng Barnie, Bernard Twumasi, Godfred Kumi Boadu, Yaa Twumwaa So-Armah, Kaku Tawiah, Phyllis |
| description | Globally, 7 million people with HIV (PWH) aged over 50 years exist. 5 million of them live in sub-Saharan Africa, the epicenter of the HIV epidemic. In Ghana, every 1 in 6 PWH is aged over 50 years. However, access to geriatric health care is grossly limited in Ghana and the sub-Saharan Africa region. This has resulted in a lack of focus on geriatric syndromes, a multi-factorial clinical condition common in older PWH, that do not fit discrete disease categories. Consequently, this gap threatens the life expectancy for aging PWH, necessitating the need to promptly fill it. The KNUST Aging and HIV Outcomes (KAHO) study will help identify priorities and opportunities for developing an effective integrated model of HIV and geriatric healthcare in Ghana.
The KAHO study will recruit 151 PWH aged 50 years and older at the Infectious Disease Unit (IDU) of the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST). The study will be conducted over a 2-year period and participants will be seen at months 0, 6 and 12. Participants at each visit will be taken through assessments and questionnaires on geriatric health, cognition, social vulnerability, HIV-related conditions and they will provide biospecimens for laboratory testing. We will also conduct semi-structured qualitative interviews of PWH, healthcare providers, policy makers and study research assistants. Quantitative data will be analyzed using one sample proportion test and linear regression models appropriately. The Levesque's framework will be used as a guide to analyze qualitative data. |
| doi_str_mv | 10.1371/journal.pone.0307719 |
| format | Article |
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The KAHO study will recruit 151 PWH aged 50 years and older at the Infectious Disease Unit (IDU) of the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST). The study will be conducted over a 2-year period and participants will be seen at months 0, 6 and 12. Participants at each visit will be taken through assessments and questionnaires on geriatric health, cognition, social vulnerability, HIV-related conditions and they will provide biospecimens for laboratory testing. We will also conduct semi-structured qualitative interviews of PWH, healthcare providers, policy makers and study research assistants. Quantitative data will be analyzed using one sample proportion test and linear regression models appropriately. The Levesque's framework will be used as a guide to analyze qualitative data.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0307719</identifier><identifier>PMID: 39150927</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Aged ; Aging ; Analysis ; Chronic illnesses ; Cognition ; Communicable diseases ; Comorbidity ; Data analysis ; Diabetes ; Earthquakes ; Female ; Forecasts and trends ; Frailty ; Geriatric psychiatry ; Geriatrics ; Ghana ; Ghana - epidemiology ; Health aspects ; Health care ; Health care industry ; HIV ; HIV (Viruses) ; HIV Infections - epidemiology ; Hospitals ; Human immunodeficiency virus ; Humans ; Hypertension ; Infectious diseases ; Laboratory tests ; Life expectancy ; Life span ; Male ; Medical records ; Mental depression ; Metabolic disorders ; Middle Aged ; Nkrumah, Kwame (1909-1972) ; Public health ; Qualitative analysis ; Regression analysis ; Regression models ; Social interactions</subject><ispartof>PloS one, 2024-08, Vol.19 (8), p.e0307719</ispartof><rights>Copyright: © 2024 Werekuu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2024 Public Library of Science</rights><rights>2024 Werekuu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 Werekuu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-0961-4434 ; 0000-0003-2321-387X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,866,2104,23873,27931,27932</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39150927$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Werekuu, Alex</creatorcontrib><creatorcontrib>Ayisi-Boateng, Nana Kwame</creatorcontrib><creatorcontrib>Tagoe, Nadia</creatorcontrib><creatorcontrib>Opoku, Douglas Aninng</creatorcontrib><creatorcontrib>Barnie, Bernard</creatorcontrib><creatorcontrib>Twumasi, Godfred Kumi</creatorcontrib><creatorcontrib>Boadu, Yaa Twumwaa</creatorcontrib><creatorcontrib>So-Armah, Kaku</creatorcontrib><creatorcontrib>Tawiah, Phyllis</creatorcontrib><title>KNUST aging and human immunodeficiency virus outcomes-Study protocol</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Globally, 7 million people with HIV (PWH) aged over 50 years exist. 5 million of them live in sub-Saharan Africa, the epicenter of the HIV epidemic. In Ghana, every 1 in 6 PWH is aged over 50 years. However, access to geriatric health care is grossly limited in Ghana and the sub-Saharan Africa region. This has resulted in a lack of focus on geriatric syndromes, a multi-factorial clinical condition common in older PWH, that do not fit discrete disease categories. Consequently, this gap threatens the life expectancy for aging PWH, necessitating the need to promptly fill it. The KNUST Aging and HIV Outcomes (KAHO) study will help identify priorities and opportunities for developing an effective integrated model of HIV and geriatric healthcare in Ghana.
The KAHO study will recruit 151 PWH aged 50 years and older at the Infectious Disease Unit (IDU) of the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST). The study will be conducted over a 2-year period and participants will be seen at months 0, 6 and 12. Participants at each visit will be taken through assessments and questionnaires on geriatric health, cognition, social vulnerability, HIV-related conditions and they will provide biospecimens for laboratory testing. We will also conduct semi-structured qualitative interviews of PWH, healthcare providers, policy makers and study research assistants. Quantitative data will be analyzed using one sample proportion test and linear regression models appropriately. The Levesque's framework will be used as a guide to analyze qualitative data.</description><subject>Aged</subject><subject>Aging</subject><subject>Analysis</subject><subject>Chronic illnesses</subject><subject>Cognition</subject><subject>Communicable diseases</subject><subject>Comorbidity</subject><subject>Data analysis</subject><subject>Diabetes</subject><subject>Earthquakes</subject><subject>Female</subject><subject>Forecasts and trends</subject><subject>Frailty</subject><subject>Geriatric psychiatry</subject><subject>Geriatrics</subject><subject>Ghana</subject><subject>Ghana - epidemiology</subject><subject>Health aspects</subject><subject>Health care</subject><subject>Health care industry</subject><subject>HIV</subject><subject>HIV (Viruses)</subject><subject>HIV Infections - epidemiology</subject><subject>Hospitals</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Infectious diseases</subject><subject>Laboratory tests</subject><subject>Life expectancy</subject><subject>Life span</subject><subject>Male</subject><subject>Medical records</subject><subject>Mental depression</subject><subject>Metabolic disorders</subject><subject>Middle Aged</subject><subject>Nkrumah, Kwame (1909-1972)</subject><subject>Public health</subject><subject>Qualitative analysis</subject><subject>Regression analysis</subject><subject>Regression models</subject><subject>Social 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Aninng</au><au>Barnie, Bernard</au><au>Twumasi, Godfred Kumi</au><au>Boadu, Yaa Twumwaa</au><au>So-Armah, Kaku</au><au>Tawiah, Phyllis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>KNUST aging and human immunodeficiency virus outcomes-Study protocol</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2024-08-16</date><risdate>2024</risdate><volume>19</volume><issue>8</issue><spage>e0307719</spage><pages>e0307719-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Globally, 7 million people with HIV (PWH) aged over 50 years exist. 5 million of them live in sub-Saharan Africa, the epicenter of the HIV epidemic. In Ghana, every 1 in 6 PWH is aged over 50 years. However, access to geriatric health care is grossly limited in Ghana and the sub-Saharan Africa region. This has resulted in a lack of focus on geriatric syndromes, a multi-factorial clinical condition common in older PWH, that do not fit discrete disease categories. Consequently, this gap threatens the life expectancy for aging PWH, necessitating the need to promptly fill it. The KNUST Aging and HIV Outcomes (KAHO) study will help identify priorities and opportunities for developing an effective integrated model of HIV and geriatric healthcare in Ghana.
The KAHO study will recruit 151 PWH aged 50 years and older at the Infectious Disease Unit (IDU) of the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST). The study will be conducted over a 2-year period and participants will be seen at months 0, 6 and 12. Participants at each visit will be taken through assessments and questionnaires on geriatric health, cognition, social vulnerability, HIV-related conditions and they will provide biospecimens for laboratory testing. We will also conduct semi-structured qualitative interviews of PWH, healthcare providers, policy makers and study research assistants. Quantitative data will be analyzed using one sample proportion test and linear regression models appropriately. The Levesque's framework will be used as a guide to analyze qualitative data.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>39150927</pmid><doi>10.1371/journal.pone.0307719</doi><tpages>e0307719</tpages><orcidid>https://orcid.org/0000-0002-0961-4434</orcidid><orcidid>https://orcid.org/0000-0003-2321-387X</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Aged Aging Analysis Chronic illnesses Cognition Communicable diseases Comorbidity Data analysis Diabetes Earthquakes Female Forecasts and trends Frailty Geriatric psychiatry Geriatrics Ghana Ghana - epidemiology Health aspects Health care Health care industry HIV HIV (Viruses) HIV Infections - epidemiology Hospitals Human immunodeficiency virus Humans Hypertension Infectious diseases Laboratory tests Life expectancy Life span Male Medical records Mental depression Metabolic disorders Middle Aged Nkrumah, Kwame (1909-1972) Public health Qualitative analysis Regression analysis Regression models Social interactions |
| title | KNUST aging and human immunodeficiency virus outcomes-Study protocol |
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