Assessment of polymeric mucin-drug interactions

Mucosal-delivered drugs have to pass through the mucus layer before absorption through the epithelial cell membrane. Although there has been increasing interest in polymeric mucins, a major structural component of mucus, potentially acting as important physiological regulators of mucosal drug absorp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2024-06, Vol.19 (6), p.e0306058
Hauptverfasser:	Kishimoto, Hisanao, Ridley, Caroline, Inoue, Katsuhisa, Thornton, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Absorption Binding Biology and Life Sciences Cell membranes Clonal deletion Complications and side effects CRISPR Cyclosporin A Cyclosporine Cyclosporine - pharmacology Cytotoxicity Drug development Drug interaction Drug Interactions Drugs Epithelial cells Epithelium Fluorescence Humans Medicine and Health Sciences Mucin Mucin 5AC - genetics Mucin 5AC - metabolism Mucin-2 - genetics Mucin-2 - metabolism Mucin-5B - genetics Mucin-5B - metabolism Mucins Mucins - metabolism Mucosa Mucus Paclitaxel Paclitaxel - metabolism Paclitaxel - pharmacology Peptides Physical Sciences Physiological aspects Physiology Protein Binding Rifampin Rifampin - pharmacology Sedimentation & deposition Theophylline Viscoelasticity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!