Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention
Indigenous women are vulnerable to cervical cancer. Screening is a strategy to reduce the burden of the disease. To evaluate the prevalence profile of cervical cancer screening cytological results in Brazilian indigenous women by age and frequency of tests compared to non-indigenous women. A cross-s...
Gespeichert in:
| Veröffentlicht in: | PloS one 2023-12, Vol.18 (12), p.e0294956-e0294956 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0294956 |
|---|---|
| container_issue | 12 |
| container_start_page | e0294956 |
| container_title | PloS one |
| container_volume | 18 |
| creator | Novais, Iria Ribeiro Coelho, Camila Olegario Machado, Helymar Costa Surita, Fernanda Zeferino, Luiz Carlos Vale, Diama Bhadra |
| description | Indigenous women are vulnerable to cervical cancer. Screening is a strategy to reduce the burden of the disease.
To evaluate the prevalence profile of cervical cancer screening cytological results in Brazilian indigenous women by age and frequency of tests compared to non-indigenous women.
A cross-sectional study evaluating the prevalences of screening test results in indigenous women assisted in the Brazilian Amazon from 2007 to 2019 (3,231 tests), compared to non-indigenous women (698,415 tests). The main outcome was the cytological result. Other variables were frequency, age groups, and population. The frequency was categorized as "1st test", the first test performed by the women in their lifetime, or "screening test," tests from women who had previously participated in screening. Analyzes were based on prevalences by age group and population. We used Prevalence Ratios (PR) and 95% Confidence Intervals for risks and linear regression for trends.
Data from the 1st test showed a higher prevalence of Low-grade Squamous Intraepithelial Lesion (LSIL) in indigenous women. Peaks were observed in indigenous under 25, 35 to 39, 45 to 49, and 60 to 64. The prevalence of High-grade Squamous Intraepithelial Lesion or more severe (HSIL+) was low in both groups in women younger than 25. The indigenous HSIL+ prevalence curve showed a rapid increase, reaching peaks in women from 25 to 34 years, following a slight decrease and a plateau. In screening tests, HSIL+ was more prevalent in indigenous from 25 to 39 (PR 4.0,2.3;6.8) and 40 to 64 (PR 3.8,1.6;9.0). In indigenous, the PR of HSIL+ results in screening tests over 1st tests showed no screening effect in all age groups. In non-indigenous, there was a significant effect toward protection in the age groups over 25.
This screening study of indigenous women from diverse ethnicities showed a higher prevalence of cytological LSIL and HSIl+ than in non-indigenous women. The protective screening effect in reducing HSIL+ prevalence was not observed in indigenous. |
| doi_str_mv | 10.1371/journal.pone.0294956 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_3072929714</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A775736361</galeid><doaj_id>oai_doaj_org_article_65ec8866ec5045f5a787e50e8c828236</doaj_id><sourcerecordid>A775736361</sourcerecordid><originalsourceid>FETCH-LOGICAL-c637t-5cb5c74a8b795550d18ecf471a11d6ff96268bd1df6a09c35e4752960014f2b3</originalsourceid><addsrcrecordid>eNqNkl2L1DAUhoso7rr6D0QDgujFjEmbj9a7cfBjYGFBB29Dmp7MZGiTmrS7uuB_N-N0lx3ZCwkk4fC854Q3b5Y9J3hOCkHe7fwYnGrnvXcwx3lFK8YfZKekKvIZz3Hx8M79JHsS4w5jVpScP85OihJzSit6mv1eQri0WrVIK6choKgDgLNug6xDH4K6tq1VDi06de0dWrnGbsD5MaIr34F7j9b-SoUmomELSTGAi9akfoNNtDeoH-vWatT7tFuIyPiA-gCX4PbE0-yRUW2EZ9N5lq0_fVwvv8zOLz6vlovzmeaFGGZM10wLqspaVIwx3JAStKGCKEIabkzFc17WDWkMV7jSBQMqWF5xjAk1eV2cZS8PbfvWRzkZF2WBRV7llSA0EasD0Xi1k32wnQq_pFdW_i34sJEqDFa3IDkDXSYbQTNMmWFKlAIYhlKXeZkXPPV6M00L_scIcZCdjRraVjlIxsm8Sr_FOBU4oa_-Qe9_3ERtVJpvnfFDUHrfVC6EYCLN5CRR83uotBrorE4hMTbVjwRvjwSJGeDnsFFjjHL17ev_sxffj9nXd9gtqHbYRt-O-w-PxyA9gDr4GAOYW-MJlvuM37gh9xmXU8aT7MVk2lh30NyKbkJd_AEta_Y0</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3072929714</pqid></control><display><type>article</type><title>Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Novais, Iria Ribeiro ; Coelho, Camila Olegario ; Machado, Helymar Costa ; Surita, Fernanda ; Zeferino, Luiz Carlos ; Vale, Diama Bhadra</creator><contributor>Vallinoto, Antonio Carlos Rosario</contributor><creatorcontrib>Novais, Iria Ribeiro ; Coelho, Camila Olegario ; Machado, Helymar Costa ; Surita, Fernanda ; Zeferino, Luiz Carlos ; Vale, Diama Bhadra ; Vallinoto, Antonio Carlos Rosario</creatorcontrib><description>Indigenous women are vulnerable to cervical cancer. Screening is a strategy to reduce the burden of the disease.
To evaluate the prevalence profile of cervical cancer screening cytological results in Brazilian indigenous women by age and frequency of tests compared to non-indigenous women.
A cross-sectional study evaluating the prevalences of screening test results in indigenous women assisted in the Brazilian Amazon from 2007 to 2019 (3,231 tests), compared to non-indigenous women (698,415 tests). The main outcome was the cytological result. Other variables were frequency, age groups, and population. The frequency was categorized as "1st test", the first test performed by the women in their lifetime, or "screening test," tests from women who had previously participated in screening. Analyzes were based on prevalences by age group and population. We used Prevalence Ratios (PR) and 95% Confidence Intervals for risks and linear regression for trends.
Data from the 1st test showed a higher prevalence of Low-grade Squamous Intraepithelial Lesion (LSIL) in indigenous women. Peaks were observed in indigenous under 25, 35 to 39, 45 to 49, and 60 to 64. The prevalence of High-grade Squamous Intraepithelial Lesion or more severe (HSIL+) was low in both groups in women younger than 25. The indigenous HSIL+ prevalence curve showed a rapid increase, reaching peaks in women from 25 to 34 years, following a slight decrease and a plateau. In screening tests, HSIL+ was more prevalent in indigenous from 25 to 39 (PR 4.0,2.3;6.8) and 40 to 64 (PR 3.8,1.6;9.0). In indigenous, the PR of HSIL+ results in screening tests over 1st tests showed no screening effect in all age groups. In non-indigenous, there was a significant effect toward protection in the age groups over 25.
This screening study of indigenous women from diverse ethnicities showed a higher prevalence of cytological LSIL and HSIl+ than in non-indigenous women. The protective screening effect in reducing HSIL+ prevalence was not observed in indigenous.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0294956</identifier><identifier>PMID: 38064494</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Age ; Age groups ; Analysis ; Cancer ; Cancer screening ; Cellular biology ; Cervical cancer ; Confidence intervals ; Diagnosis ; Ethnicity ; Health aspects ; Health care ; Hysterectomy ; Indigenous peoples ; Laboratories ; Lesions ; Medical screening ; Minority women ; Mortality ; Native peoples ; Nonprofit organizations ; Prevention ; Public health ; Public policy ; Risk factors ; Statistical analysis ; Statistics ; Vaccines ; Variables ; Women ; Womens health</subject><ispartof>PloS one, 2023-12, Vol.18 (12), p.e0294956-e0294956</ispartof><rights>Copyright: © 2023 Novais et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Novais et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Novais et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c637t-5cb5c74a8b795550d18ecf471a11d6ff96268bd1df6a09c35e4752960014f2b3</citedby><cites>FETCH-LOGICAL-c637t-5cb5c74a8b795550d18ecf471a11d6ff96268bd1df6a09c35e4752960014f2b3</cites><orcidid>0009-0007-6019-3229 ; 0000-0003-2423-0225 ; 0000-0001-5823-3278 ; 0000-0003-4335-0337</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,865,2103,2929,23871,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38064494$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Vallinoto, Antonio Carlos Rosario</contributor><creatorcontrib>Novais, Iria Ribeiro</creatorcontrib><creatorcontrib>Coelho, Camila Olegario</creatorcontrib><creatorcontrib>Machado, Helymar Costa</creatorcontrib><creatorcontrib>Surita, Fernanda</creatorcontrib><creatorcontrib>Zeferino, Luiz Carlos</creatorcontrib><creatorcontrib>Vale, Diama Bhadra</creatorcontrib><title>Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Indigenous women are vulnerable to cervical cancer. Screening is a strategy to reduce the burden of the disease.
To evaluate the prevalence profile of cervical cancer screening cytological results in Brazilian indigenous women by age and frequency of tests compared to non-indigenous women.
A cross-sectional study evaluating the prevalences of screening test results in indigenous women assisted in the Brazilian Amazon from 2007 to 2019 (3,231 tests), compared to non-indigenous women (698,415 tests). The main outcome was the cytological result. Other variables were frequency, age groups, and population. The frequency was categorized as "1st test", the first test performed by the women in their lifetime, or "screening test," tests from women who had previously participated in screening. Analyzes were based on prevalences by age group and population. We used Prevalence Ratios (PR) and 95% Confidence Intervals for risks and linear regression for trends.
Data from the 1st test showed a higher prevalence of Low-grade Squamous Intraepithelial Lesion (LSIL) in indigenous women. Peaks were observed in indigenous under 25, 35 to 39, 45 to 49, and 60 to 64. The prevalence of High-grade Squamous Intraepithelial Lesion or more severe (HSIL+) was low in both groups in women younger than 25. The indigenous HSIL+ prevalence curve showed a rapid increase, reaching peaks in women from 25 to 34 years, following a slight decrease and a plateau. In screening tests, HSIL+ was more prevalent in indigenous from 25 to 39 (PR 4.0,2.3;6.8) and 40 to 64 (PR 3.8,1.6;9.0). In indigenous, the PR of HSIL+ results in screening tests over 1st tests showed no screening effect in all age groups. In non-indigenous, there was a significant effect toward protection in the age groups over 25.
This screening study of indigenous women from diverse ethnicities showed a higher prevalence of cytological LSIL and HSIl+ than in non-indigenous women. The protective screening effect in reducing HSIL+ prevalence was not observed in indigenous.</description><subject>Age</subject><subject>Age groups</subject><subject>Analysis</subject><subject>Cancer</subject><subject>Cancer screening</subject><subject>Cellular biology</subject><subject>Cervical cancer</subject><subject>Confidence intervals</subject><subject>Diagnosis</subject><subject>Ethnicity</subject><subject>Health aspects</subject><subject>Health care</subject><subject>Hysterectomy</subject><subject>Indigenous peoples</subject><subject>Laboratories</subject><subject>Lesions</subject><subject>Medical screening</subject><subject>Minority women</subject><subject>Mortality</subject><subject>Native peoples</subject><subject>Nonprofit organizations</subject><subject>Prevention</subject><subject>Public health</subject><subject>Public policy</subject><subject>Risk factors</subject><subject>Statistical analysis</subject><subject>Statistics</subject><subject>Vaccines</subject><subject>Variables</subject><subject>Women</subject><subject>Womens health</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl2L1DAUhoso7rr6D0QDgujFjEmbj9a7cfBjYGFBB29Dmp7MZGiTmrS7uuB_N-N0lx3ZCwkk4fC854Q3b5Y9J3hOCkHe7fwYnGrnvXcwx3lFK8YfZKekKvIZz3Hx8M79JHsS4w5jVpScP85OihJzSit6mv1eQri0WrVIK6choKgDgLNug6xDH4K6tq1VDi06de0dWrnGbsD5MaIr34F7j9b-SoUmomELSTGAi9akfoNNtDeoH-vWatT7tFuIyPiA-gCX4PbE0-yRUW2EZ9N5lq0_fVwvv8zOLz6vlovzmeaFGGZM10wLqspaVIwx3JAStKGCKEIabkzFc17WDWkMV7jSBQMqWF5xjAk1eV2cZS8PbfvWRzkZF2WBRV7llSA0EasD0Xi1k32wnQq_pFdW_i34sJEqDFa3IDkDXSYbQTNMmWFKlAIYhlKXeZkXPPV6M00L_scIcZCdjRraVjlIxsm8Sr_FOBU4oa_-Qe9_3ERtVJpvnfFDUHrfVC6EYCLN5CRR83uotBrorE4hMTbVjwRvjwSJGeDnsFFjjHL17ev_sxffj9nXd9gtqHbYRt-O-w-PxyA9gDr4GAOYW-MJlvuM37gh9xmXU8aT7MVk2lh30NyKbkJd_AEta_Y0</recordid><startdate>20231208</startdate><enddate>20231208</enddate><creator>Novais, Iria Ribeiro</creator><creator>Coelho, Camila Olegario</creator><creator>Machado, Helymar Costa</creator><creator>Surita, Fernanda</creator><creator>Zeferino, Luiz Carlos</creator><creator>Vale, Diama Bhadra</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>DOA</scope><orcidid>https://orcid.org/0009-0007-6019-3229</orcidid><orcidid>https://orcid.org/0000-0003-2423-0225</orcidid><orcidid>https://orcid.org/0000-0001-5823-3278</orcidid><orcidid>https://orcid.org/0000-0003-4335-0337</orcidid></search><sort><creationdate>20231208</creationdate><title>Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention</title><author>Novais, Iria Ribeiro ; Coelho, Camila Olegario ; Machado, Helymar Costa ; Surita, Fernanda ; Zeferino, Luiz Carlos ; Vale, Diama Bhadra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c637t-5cb5c74a8b795550d18ecf471a11d6ff96268bd1df6a09c35e4752960014f2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Age</topic><topic>Age groups</topic><topic>Analysis</topic><topic>Cancer</topic><topic>Cancer screening</topic><topic>Cellular biology</topic><topic>Cervical cancer</topic><topic>Confidence intervals</topic><topic>Diagnosis</topic><topic>Ethnicity</topic><topic>Health aspects</topic><topic>Health care</topic><topic>Hysterectomy</topic><topic>Indigenous peoples</topic><topic>Laboratories</topic><topic>Lesions</topic><topic>Medical screening</topic><topic>Minority women</topic><topic>Mortality</topic><topic>Native peoples</topic><topic>Nonprofit organizations</topic><topic>Prevention</topic><topic>Public health</topic><topic>Public policy</topic><topic>Risk factors</topic><topic>Statistical analysis</topic><topic>Statistics</topic><topic>Vaccines</topic><topic>Variables</topic><topic>Women</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Novais, Iria Ribeiro</creatorcontrib><creatorcontrib>Coelho, Camila Olegario</creatorcontrib><creatorcontrib>Machado, Helymar Costa</creatorcontrib><creatorcontrib>Surita, Fernanda</creatorcontrib><creatorcontrib>Zeferino, Luiz Carlos</creatorcontrib><creatorcontrib>Vale, Diama Bhadra</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>Proquest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Novais, Iria Ribeiro</au><au>Coelho, Camila Olegario</au><au>Machado, Helymar Costa</au><au>Surita, Fernanda</au><au>Zeferino, Luiz Carlos</au><au>Vale, Diama Bhadra</au><au>Vallinoto, Antonio Carlos Rosario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2023-12-08</date><risdate>2023</risdate><volume>18</volume><issue>12</issue><spage>e0294956</spage><epage>e0294956</epage><pages>e0294956-e0294956</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Indigenous women are vulnerable to cervical cancer. Screening is a strategy to reduce the burden of the disease.
To evaluate the prevalence profile of cervical cancer screening cytological results in Brazilian indigenous women by age and frequency of tests compared to non-indigenous women.
A cross-sectional study evaluating the prevalences of screening test results in indigenous women assisted in the Brazilian Amazon from 2007 to 2019 (3,231 tests), compared to non-indigenous women (698,415 tests). The main outcome was the cytological result. Other variables were frequency, age groups, and population. The frequency was categorized as "1st test", the first test performed by the women in their lifetime, or "screening test," tests from women who had previously participated in screening. Analyzes were based on prevalences by age group and population. We used Prevalence Ratios (PR) and 95% Confidence Intervals for risks and linear regression for trends.
Data from the 1st test showed a higher prevalence of Low-grade Squamous Intraepithelial Lesion (LSIL) in indigenous women. Peaks were observed in indigenous under 25, 35 to 39, 45 to 49, and 60 to 64. The prevalence of High-grade Squamous Intraepithelial Lesion or more severe (HSIL+) was low in both groups in women younger than 25. The indigenous HSIL+ prevalence curve showed a rapid increase, reaching peaks in women from 25 to 34 years, following a slight decrease and a plateau. In screening tests, HSIL+ was more prevalent in indigenous from 25 to 39 (PR 4.0,2.3;6.8) and 40 to 64 (PR 3.8,1.6;9.0). In indigenous, the PR of HSIL+ results in screening tests over 1st tests showed no screening effect in all age groups. In non-indigenous, there was a significant effect toward protection in the age groups over 25.
This screening study of indigenous women from diverse ethnicities showed a higher prevalence of cytological LSIL and HSIl+ than in non-indigenous women. The protective screening effect in reducing HSIL+ prevalence was not observed in indigenous.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>38064494</pmid><doi>10.1371/journal.pone.0294956</doi><tpages>e0294956</tpages><orcidid>https://orcid.org/0009-0007-6019-3229</orcidid><orcidid>https://orcid.org/0000-0003-2423-0225</orcidid><orcidid>https://orcid.org/0000-0001-5823-3278</orcidid><orcidid>https://orcid.org/0000-0003-4335-0337</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2023-12, Vol.18 (12), p.e0294956-e0294956 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_3072929714 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS) Journals Open Access; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Age Age groups Analysis Cancer Cancer screening Cellular biology Cervical cancer Confidence intervals Diagnosis Ethnicity Health aspects Health care Hysterectomy Indigenous peoples Laboratories Lesions Medical screening Minority women Mortality Native peoples Nonprofit organizations Prevention Public health Public policy Risk factors Statistical analysis Statistics Vaccines Variables Women Womens health |
| title | Cervical cancer screening in Brazilian Amazon Indigenous women: Towards the intensification of public policies for prevention |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T16%3A49%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cervical%20cancer%20screening%20in%20Brazilian%20Amazon%20Indigenous%20women:%20Towards%20the%20intensification%20of%20public%20policies%20for%20prevention&rft.jtitle=PloS%20one&rft.au=Novais,%20Iria%20Ribeiro&rft.date=2023-12-08&rft.volume=18&rft.issue=12&rft.spage=e0294956&rft.epage=e0294956&rft.pages=e0294956-e0294956&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0294956&rft_dat=%3Cgale_plos_%3EA775736361%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3072929714&rft_id=info:pmid/38064494&rft_galeid=A775736361&rft_doaj_id=oai_doaj_org_article_65ec8866ec5045f5a787e50e8c828236&rfr_iscdi=true |