Prognostic impact of suspicious extraabdominal lymph nodes on patient survival in advanced ovarian cancer
To evaluate the clinical impact of suspicious extra-abdominal lymph nodes (EALNs) identified preoperatively on CT and/or PET/CT images in advanced ovarian cancer. A retrospective study was conducted with 122 patients diagnosed with stage III or IV ovarian cancer with preoperative CT and/or PET/CT im...
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| creator | Park, Kena Kwon, Ji Young Song, Jeong Min Pyeon, Seung Yeon Lee, Seon Hwa Chung, Young Shin Lee, Jong-Min |
| description | To evaluate the clinical impact of suspicious extra-abdominal lymph nodes (EALNs) identified preoperatively on CT and/or PET/CT images in advanced ovarian cancer.
A retrospective study was conducted with 122 patients diagnosed with stage III or IV ovarian cancer with preoperative CT and/or PET/CT images from 2006 to 2022. Imaging studies were evaluated for the presence, size and location of suspicious EALNs. Suspicious lymph node enlargement was defined by a cut-off ≥5mm short-axis dimension on CT and/or lesions with maximum standardized uptake values of ≥2.5 on PET/CT. This study only included patients who did not have their EALNs surgically removed.
A total 109 patients met the inclusion criteria; 36 (33%) had suspicious EALNs and were categorized as "node-positive". The median overall survival (OS) was 45.73 months for the "node-positive" and 46.50 months for the "node-negative" patients (HR 1.17, 95% CI 0.68-2.00, p = 0.579). In multivariate analysis, after adjusting for other variables selected by process of backward elimination using a significance level of p |
| doi_str_mv | 10.1371/journal.pone.0299205 |
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A retrospective study was conducted with 122 patients diagnosed with stage III or IV ovarian cancer with preoperative CT and/or PET/CT images from 2006 to 2022. Imaging studies were evaluated for the presence, size and location of suspicious EALNs. Suspicious lymph node enlargement was defined by a cut-off ≥5mm short-axis dimension on CT and/or lesions with maximum standardized uptake values of ≥2.5 on PET/CT. This study only included patients who did not have their EALNs surgically removed.
A total 109 patients met the inclusion criteria; 36 (33%) had suspicious EALNs and were categorized as "node-positive". The median overall survival (OS) was 45.73 months for the "node-positive" and 46.50 months for the "node-negative" patients (HR 1.17, 95% CI 0.68-2.00, p = 0.579). In multivariate analysis, after adjusting for other variables selected by process of backward elimination using a significance level of p<0.20, suspicious EALNs still showed no clinical significance on OS (aHR 1.20, 95% CI 0.67-2.13, p = 0.537) as well as progression-free survival (aHR 1.43, 95% CI 0.85-2.41, p = 0.174). Old age (aHR 2.23, 95% CI 1.28-3.89, p = 0.005) and platinum resistance (aHR 1.92, 95% CI 1.10-3.36, p = 0.023) affects adversely on OS.
Suspicious EALNs did not worsen the prognosis of patients with advanced ovarian cancer. However, its impact on survival is not yet clarified. Further investigation is required to assess the clinical significance of suspicious EALNs on preoperative imaging studies.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0299205</identifier><identifier>PMID: 38805507</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abdomen ; Adult ; Aged ; Aged, 80 and over ; Biology and Life Sciences ; Cancer ; Cancer patients ; Chemotherapy ; Computed tomography ; CT imaging ; Data collection ; Development and progression ; Disease ; Female ; Humans ; Lymph nodes ; Lymph Nodes - diagnostic imaging ; Lymph Nodes - pathology ; Lymphatic Metastasis ; Lymphatic system ; Medical imaging ; Medical prognosis ; Medicine and Health Sciences ; Middle Aged ; Multivariate analysis ; Neoplasm Staging ; Oncology, Experimental ; Ovarian cancer ; Ovarian Neoplasms - diagnosis ; Ovarian Neoplasms - diagnostic imaging ; Ovarian Neoplasms - mortality ; Ovarian Neoplasms - pathology ; Ovarian Neoplasms - surgery ; Patient outcomes ; Patients ; PET imaging ; Physical Sciences ; Platinum ; Pleural effusion ; Positron emission ; Positron Emission Tomography Computed Tomography - methods ; Prognosis ; Research and Analysis Methods ; Retrospective Studies ; Surgery ; Survival ; Tomography ; Tomography, X-Ray Computed</subject><ispartof>PloS one, 2024-05, Vol.19 (5), p.e0299205-e0299205</ispartof><rights>Copyright: © 2024 Park et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2024 Public Library of Science</rights><rights>2024 Park et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2024 Park et al 2024 Park et al</rights><rights>2024 Park et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c572t-63e41fe6dce110a879a94371445132ce68df1835da2f32c132948033b96febdb3</cites><orcidid>0000-0002-7219-6386 ; 0009-0007-5775-0995 ; 0000-0001-8601-1701 ; 0000-0002-0562-5443 ; 0000-0003-4640-963X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132458/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11132458/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38805507$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Kena</creatorcontrib><creatorcontrib>Kwon, Ji Young</creatorcontrib><creatorcontrib>Song, Jeong Min</creatorcontrib><creatorcontrib>Pyeon, Seung Yeon</creatorcontrib><creatorcontrib>Lee, Seon Hwa</creatorcontrib><creatorcontrib>Chung, Young Shin</creatorcontrib><creatorcontrib>Lee, Jong-Min</creatorcontrib><title>Prognostic impact of suspicious extraabdominal lymph nodes on patient survival in advanced ovarian cancer</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To evaluate the clinical impact of suspicious extra-abdominal lymph nodes (EALNs) identified preoperatively on CT and/or PET/CT images in advanced ovarian cancer.
A retrospective study was conducted with 122 patients diagnosed with stage III or IV ovarian cancer with preoperative CT and/or PET/CT images from 2006 to 2022. Imaging studies were evaluated for the presence, size and location of suspicious EALNs. Suspicious lymph node enlargement was defined by a cut-off ≥5mm short-axis dimension on CT and/or lesions with maximum standardized uptake values of ≥2.5 on PET/CT. This study only included patients who did not have their EALNs surgically removed.
A total 109 patients met the inclusion criteria; 36 (33%) had suspicious EALNs and were categorized as "node-positive". The median overall survival (OS) was 45.73 months for the "node-positive" and 46.50 months for the "node-negative" patients (HR 1.17, 95% CI 0.68-2.00, p = 0.579). In multivariate analysis, after adjusting for other variables selected by process of backward elimination using a significance level of p<0.20, suspicious EALNs still showed no clinical significance on OS (aHR 1.20, 95% CI 0.67-2.13, p = 0.537) as well as progression-free survival (aHR 1.43, 95% CI 0.85-2.41, p = 0.174). Old age (aHR 2.23, 95% CI 1.28-3.89, p = 0.005) and platinum resistance (aHR 1.92, 95% CI 1.10-3.36, p = 0.023) affects adversely on OS.
Suspicious EALNs did not worsen the prognosis of patients with advanced ovarian cancer. However, its impact on survival is not yet clarified. Further investigation is required to assess the clinical significance of suspicious EALNs on preoperative imaging studies.</description><subject>Abdomen</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biology and Life Sciences</subject><subject>Cancer</subject><subject>Cancer patients</subject><subject>Chemotherapy</subject><subject>Computed tomography</subject><subject>CT imaging</subject><subject>Data collection</subject><subject>Development and progression</subject><subject>Disease</subject><subject>Female</subject><subject>Humans</subject><subject>Lymph nodes</subject><subject>Lymph Nodes - diagnostic imaging</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Lymphatic system</subject><subject>Medical imaging</subject><subject>Medical prognosis</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Multivariate analysis</subject><subject>Neoplasm Staging</subject><subject>Oncology, Experimental</subject><subject>Ovarian cancer</subject><subject>Ovarian Neoplasms - diagnosis</subject><subject>Ovarian Neoplasms - diagnostic imaging</subject><subject>Ovarian Neoplasms - mortality</subject><subject>Ovarian Neoplasms - pathology</subject><subject>Ovarian Neoplasms - surgery</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>PET imaging</subject><subject>Physical Sciences</subject><subject>Platinum</subject><subject>Pleural effusion</subject><subject>Positron emission</subject><subject>Positron Emission Tomography Computed Tomography - methods</subject><subject>Prognosis</subject><subject>Research and Analysis Methods</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Survival</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1uL1DAUx4so7jr6DUQLgujDjEnTS_oky-JlYGHF22s4TZOZDG1Sk7a4395Tp7tMZR-kD2lOfud_LsmJoueUbCgr6LuDG7yFZtM5qzYkKcuEZA-ic1qyZJ0nhD08-T-LnoRwICRjPM8fR2eMc5JlpDiPzBfvdtaF3sjYtB3IPnY6DkPojDRuCLH63XuAqnatwWhxc9N2-9i6WoXY2biD3ijbo4MfzYjnxsZQj2ClqmM3gjdgYzlt_dPokYYmqGfzuop-fPzw_fLz-ur60_by4motsyLp1zlTKdUqr6WilAAvSihTrDdNM8oSqXJea8pZVkOicY-2MuWEsarMtarqiq2il0fdrnFBzF0KgpG8THiZpQSJ7ZGoHRxE500L_kY4MOKvwfmdAI8NaZTQmhU8yXVJeJIWnFSMEZbxNGHAoCgoar2fow1VqzBpi-1qFqLLE2v2YudGQSmmnmYcFd7MCt79GlToRWuCVE0DVuEFTInTgtMcL3MVvfoHvb-8mdoBVmCsdhhYTqLioigzzL7gk9bmHgq_WrVG4pvSBu0Lh7cLB2R6fBw7GEIQ229f_5-9_rlkX5-wewVNvw-uGXrjbFiC6RGU3oXglb7rMiViGonbbohpJMQ8Euj24vSG7pxuZ4D9AcHmBn0</recordid><startdate>20240528</startdate><enddate>20240528</enddate><creator>Park, Kena</creator><creator>Kwon, Ji Young</creator><creator>Song, Jeong Min</creator><creator>Pyeon, Seung Yeon</creator><creator>Lee, Seon Hwa</creator><creator>Chung, Young Shin</creator><creator>Lee, Jong-Min</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7219-6386</orcidid><orcidid>https://orcid.org/0009-0007-5775-0995</orcidid><orcidid>https://orcid.org/0000-0001-8601-1701</orcidid><orcidid>https://orcid.org/0000-0002-0562-5443</orcidid><orcidid>https://orcid.org/0000-0003-4640-963X</orcidid></search><sort><creationdate>20240528</creationdate><title>Prognostic impact of suspicious extraabdominal lymph nodes on patient survival in advanced ovarian cancer</title><author>Park, Kena ; Kwon, Ji Young ; Song, Jeong Min ; Pyeon, Seung Yeon ; Lee, Seon Hwa ; Chung, Young Shin ; Lee, Jong-Min</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c572t-63e41fe6dce110a879a94371445132ce68df1835da2f32c132948033b96febdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biology and Life Sciences</topic><topic>Cancer</topic><topic>Cancer patients</topic><topic>Chemotherapy</topic><topic>Computed tomography</topic><topic>CT imaging</topic><topic>Data collection</topic><topic>Development and progression</topic><topic>Disease</topic><topic>Female</topic><topic>Humans</topic><topic>Lymph nodes</topic><topic>Lymph Nodes - diagnostic imaging</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Lymphatic system</topic><topic>Medical imaging</topic><topic>Medical prognosis</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Multivariate analysis</topic><topic>Neoplasm Staging</topic><topic>Oncology, Experimental</topic><topic>Ovarian cancer</topic><topic>Ovarian Neoplasms - diagnosis</topic><topic>Ovarian Neoplasms - diagnostic imaging</topic><topic>Ovarian Neoplasms - mortality</topic><topic>Ovarian Neoplasms - pathology</topic><topic>Ovarian Neoplasms - surgery</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>PET imaging</topic><topic>Physical Sciences</topic><topic>Platinum</topic><topic>Pleural effusion</topic><topic>Positron emission</topic><topic>Positron Emission Tomography Computed Tomography - methods</topic><topic>Prognosis</topic><topic>Research and Analysis Methods</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Survival</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Kena</creatorcontrib><creatorcontrib>Kwon, Ji Young</creatorcontrib><creatorcontrib>Song, Jeong Min</creatorcontrib><creatorcontrib>Pyeon, Seung Yeon</creatorcontrib><creatorcontrib>Lee, Seon Hwa</creatorcontrib><creatorcontrib>Chung, Young Shin</creatorcontrib><creatorcontrib>Lee, Jong-Min</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Kena</au><au>Kwon, Ji Young</au><au>Song, Jeong Min</au><au>Pyeon, Seung Yeon</au><au>Lee, Seon Hwa</au><au>Chung, Young Shin</au><au>Lee, Jong-Min</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic impact of suspicious extraabdominal lymph nodes on patient survival in advanced ovarian cancer</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2024-05-28</date><risdate>2024</risdate><volume>19</volume><issue>5</issue><spage>e0299205</spage><epage>e0299205</epage><pages>e0299205-e0299205</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To evaluate the clinical impact of suspicious extra-abdominal lymph nodes (EALNs) identified preoperatively on CT and/or PET/CT images in advanced ovarian cancer.
A retrospective study was conducted with 122 patients diagnosed with stage III or IV ovarian cancer with preoperative CT and/or PET/CT images from 2006 to 2022. Imaging studies were evaluated for the presence, size and location of suspicious EALNs. Suspicious lymph node enlargement was defined by a cut-off ≥5mm short-axis dimension on CT and/or lesions with maximum standardized uptake values of ≥2.5 on PET/CT. This study only included patients who did not have their EALNs surgically removed.
A total 109 patients met the inclusion criteria; 36 (33%) had suspicious EALNs and were categorized as "node-positive". The median overall survival (OS) was 45.73 months for the "node-positive" and 46.50 months for the "node-negative" patients (HR 1.17, 95% CI 0.68-2.00, p = 0.579). In multivariate analysis, after adjusting for other variables selected by process of backward elimination using a significance level of p<0.20, suspicious EALNs still showed no clinical significance on OS (aHR 1.20, 95% CI 0.67-2.13, p = 0.537) as well as progression-free survival (aHR 1.43, 95% CI 0.85-2.41, p = 0.174). Old age (aHR 2.23, 95% CI 1.28-3.89, p = 0.005) and platinum resistance (aHR 1.92, 95% CI 1.10-3.36, p = 0.023) affects adversely on OS.
Suspicious EALNs did not worsen the prognosis of patients with advanced ovarian cancer. However, its impact on survival is not yet clarified. Further investigation is required to assess the clinical significance of suspicious EALNs on preoperative imaging studies.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>38805507</pmid><doi>10.1371/journal.pone.0299205</doi><tpages>e0299205</tpages><orcidid>https://orcid.org/0000-0002-7219-6386</orcidid><orcidid>https://orcid.org/0009-0007-5775-0995</orcidid><orcidid>https://orcid.org/0000-0001-8601-1701</orcidid><orcidid>https://orcid.org/0000-0002-0562-5443</orcidid><orcidid>https://orcid.org/0000-0003-4640-963X</orcidid><oa>free_for_read</oa></addata></record> |
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| language | eng |
| recordid | cdi_plos_journals_3069289540 |
| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Abdomen Adult Aged Aged, 80 and over Biology and Life Sciences Cancer Cancer patients Chemotherapy Computed tomography CT imaging Data collection Development and progression Disease Female Humans Lymph nodes Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymphatic Metastasis Lymphatic system Medical imaging Medical prognosis Medicine and Health Sciences Middle Aged Multivariate analysis Neoplasm Staging Oncology, Experimental Ovarian cancer Ovarian Neoplasms - diagnosis Ovarian Neoplasms - diagnostic imaging Ovarian Neoplasms - mortality Ovarian Neoplasms - pathology Ovarian Neoplasms - surgery Patient outcomes Patients PET imaging Physical Sciences Platinum Pleural effusion Positron emission Positron Emission Tomography Computed Tomography - methods Prognosis Research and Analysis Methods Retrospective Studies Surgery Survival Tomography Tomography, X-Ray Computed |
| title | Prognostic impact of suspicious extraabdominal lymph nodes on patient survival in advanced ovarian cancer |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T00%3A14%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prognostic%20impact%20of%20suspicious%20extraabdominal%20lymph%20nodes%20on%20patient%20survival%20in%20advanced%20ovarian%20cancer&rft.jtitle=PloS%20one&rft.au=Park,%20Kena&rft.date=2024-05-28&rft.volume=19&rft.issue=5&rft.spage=e0299205&rft.epage=e0299205&rft.pages=e0299205-e0299205&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0299205&rft_dat=%3Cgale_plos_%3EA795584789%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3069289540&rft_id=info:pmid/38805507&rft_galeid=A795584789&rft_doaj_id=oai_doaj_org_article_ff37826f90824780b330358423a3a771&rfr_iscdi=true |