"Hurts less, lasts longer"; a qualitative study on experiences of young people receiving high-dose subcutaneous injections of benzathine penicillin G to prevent rheumatic heart disease in New Zealand

Four-weekly intramuscular (IM) benzathine penicillin G (BPG) injections to prevent acute rheumatic fever (ARF) progression have remained unchanged since 1955. A Phase-I trial in healthy volunteers demonstrated the safety and tolerability of high-dose subcutaneous infusions of BPG which resulted in a...

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Veröffentlicht in:	PloS one 2024-05, Vol.19 (5), p.e0302493
Hauptverfasser:	Cooper, Julie, Enkel, Stephanie L, Moodley, Dhevindri, Dobinson, Hazel, Andersen, Erik, Kado, Joseph H, Barr, Renae K, Salman, Sam, Baker, Michael G, Carapetis, Jonathan R, Manning, Laurens, Anderson, Anneka, Bennett, Julie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Biology and Life Sciences Cardiovascular disease Cardiovascular diseases Disease prevention Dosage and administration Female Heart diseases Humans Injection Injections, Subcutaneous Lidocaine Male Medicine and Health Sciences New Zealand Pain Pain - drug therapy Pain - prevention & control Penicillin Penicillin G Penicillin G Benzathine - administration & dosage Penicillin G Benzathine - therapeutic use People and Places Prophylaxis Qualitative Research Research and Analysis Methods Rheumatic fever Rheumatic Fever - drug therapy Rheumatic Fever - prevention & control Rheumatic heart disease Rheumatic Heart Disease - drug therapy Rheumatic Heart Disease - prevention & control Safety and security measures Social Sciences Teenagers Young Adult Young adults Youth
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