Subcutaneous ketamine infusion in palliative patients for major depressive disorder (SKIPMDD)—Phase II single-arm open-label feasibility study

Background Ketamine at subanaesthetic dosages ([less than or equal to]0.5mg/kg) exhibits rapid onset (over hours to days) antidepressant effects against major depressive disorder in people who are otherwise well. However, its safety, tolerability and efficacy are not known for major depressive disor...

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Veröffentlicht in:PloS one 2023-11, Vol.18 (11), p.e0290876-e0290876
Hauptverfasser: Lee, Wei, Sheehan, Caitlin, Chye, Richard, Chang, Sungwon, Bayes, Adam, Loo, Colleen, Draper, Brian, Agar, Meera R, Currow, David C
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Sprache:eng
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