Association of urinary excretion rates of uric acid with biomarkers of kidney injury in patients with advanced chronic kidney disease

The potential influence of hyperuricemia on the genesis and progression of chronic kidney disease (CKD) remains controversial. In general, the correlation between blood levels of uric acid (UA) and the rate of progression of CKD is considered to be modest, if any, and the results of relevant trials...

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Veröffentlicht in:	PloS one 2024-06, Vol.19 (6), p.e0304105
Hauptverfasser:	López Iglesias, Antía, Blanco Pardo, Marta, Rodríguez Magariños, Catuxa, Pértega, Sonia, Sierra Castro, Diego, García Falcón, Teresa, Rodríguez-Carmona, Ana, Pérez Fontán, Miguel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Antagonists Arthritis Asymptomatic Biological markers Biology and Life Sciences Biomarkers Biomarkers - blood Biomarkers - urine Blood levels Blood pressure Care and treatment Chronic kidney failure Clinical trials Comorbidity Correlation Correlation analysis Creatinine Cross-Sectional Studies Cytokines Demographic variables Diabetes Disease Progression Excretion Female Glomerular Filtration Rate Humans Hypertension Hyperuricemia IL-1β Injuries Interleukin 1 Interleukins Kidney diseases Kidneys Life sciences Longitudinal studies Male Medicine and Health Sciences Metabolism Metabolites Middle Aged Multivariate analysis Patients Physical Sciences Plasma Plasma levels Proteins Proteinuria Regression analysis Regression models Renal function Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - urine Statins Statistical analysis Uric acid Uric Acid - blood Uric Acid - urine Urine Variables
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