Assessment of the pre-emptive effect of photobiomodulation in the postoperative period of impacted lower third molar extractions: A randomized, controlled, double-blind study protocol
Photobiomodulation is a safe option for controlling pain, edema, and trismus when applied postoperatively in third molar surgery. However, administration prior to surgery has been under-explored. This study aims to explore the effectiveness of pre-emptive photobiomodulation in reducing postoperative...
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| Veröffentlicht in: | PloS one 2024-06, Vol.19 (6), p.e0300136 |
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| creator | Salaberry, Daniel Rodríguez Bruno, Laura Hermida Cirisola, Rolf Wilhem Consolandich Longo, Priscila Larcher Chavantes, Maria Cristina Navarro, Ricardo Scarparo Gonçalves, Marcela Letícia Leal Sobral, Ana Paula Taboada Gimenez, Thais Duran, Cinthya Cosme Gutierrez Motta, Lara Jansiski Bussadori, Sandra Kalil Horliana, Anna Carolina Ratto Tempestini Mesquita Ferrari, Raquel Agnelli Fernandes, Kristianne Porta Santos |
| description | Photobiomodulation is a safe option for controlling pain, edema, and trismus when applied postoperatively in third molar surgery. However, administration prior to surgery has been under-explored. This study aims to explore the effectiveness of pre-emptive photobiomodulation in reducing postoperative edema in impacted lower third molar extractions. Two groups of healthy individuals undergoing tooth extraction will be randomly assigned: Control group receiving pre-emptive corticosteroid and simulated photobiomodulation, and Photobiomodulation Group receiving intraoral low-intensity laser and extraoral LED cluster application. The primary outcome will be postoperative edema after 48 h. The secondary outcomes will be pain, trismus dysphagia, and analgesic intake (paracetamol). These outcomes will be assessed at baseline as well as two and seven days after surgery. Adverse effects will be recorded. Data will be presented as means ± SD and a p-value < 0.05 will be indicative of statistical significance. |
| doi_str_mv | 10.1371/journal.pone.0300136 |
| format | Article |
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However, administration prior to surgery has been under-explored. This study aims to explore the effectiveness of pre-emptive photobiomodulation in reducing postoperative edema in impacted lower third molar extractions. Two groups of healthy individuals undergoing tooth extraction will be randomly assigned: Control group receiving pre-emptive corticosteroid and simulated photobiomodulation, and Photobiomodulation Group receiving intraoral low-intensity laser and extraoral LED cluster application. The primary outcome will be postoperative edema after 48 h. The secondary outcomes will be pain, trismus dysphagia, and analgesic intake (paracetamol). These outcomes will be assessed at baseline as well as two and seven days after surgery. Adverse effects will be recorded. 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However, administration prior to surgery has been under-explored. This study aims to explore the effectiveness of pre-emptive photobiomodulation in reducing postoperative edema in impacted lower third molar extractions. Two groups of healthy individuals undergoing tooth extraction will be randomly assigned: Control group receiving pre-emptive corticosteroid and simulated photobiomodulation, and Photobiomodulation Group receiving intraoral low-intensity laser and extraoral LED cluster application. The primary outcome will be postoperative edema after 48 h. The secondary outcomes will be pain, trismus dysphagia, and analgesic intake (paracetamol). These outcomes will be assessed at baseline as well as two and seven days after surgery. Adverse effects will be recorded. Data will be presented as means ± SD and a p-value < 0.05 will be indicative of statistical significance.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>38885236</pmid><doi>10.1371/journal.pone.0300136</doi><orcidid>https://orcid.org/0000-0001-7708-5186</orcidid><orcidid>https://orcid.org/0000-0001-9055-1524</orcidid><orcidid>https://orcid.org/0000-0001-7156-9286</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2024-06, Vol.19 (6), p.e0300136 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_3069264057 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adult Analgesics Analysis Anti-inflammatory agents Biology and Life Sciences Calibration Care and treatment Corticosteroids Double-Blind Method Drugs Dysphagia Edema Edema - etiology Edema - prevention & control Engineering and Technology Female Humans Lasers Light-emitting diodes Low-Level Light Therapy - methods Male Medicine and Health Sciences Molar, Third - surgery Pain Pain, Postoperative - prevention & control Paracetamol Patient compliance Patients Postoperative Complications - etiology Postoperative Complications - prevention & control Postoperative Period Research ethics Study Protocol Surgery Surgical outcomes Tooth Extraction - adverse effects Tooth Extraction - methods Tooth extractions Tooth, Impacted - surgery |
| title | Assessment of the pre-emptive effect of photobiomodulation in the postoperative period of impacted lower third molar extractions: A randomized, controlled, double-blind study protocol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T17%3A58%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%20the%20pre-emptive%20effect%20of%20photobiomodulation%20in%20the%20postoperative%20period%20of%20impacted%20lower%20third%20molar%20extractions:%20A%20randomized,%20controlled,%20double-blind%20study%20protocol&rft.jtitle=PloS%20one&rft.au=Salaberry,%20Daniel%20Rodr%C3%ADguez&rft.date=2024-06-17&rft.volume=19&rft.issue=6&rft.spage=e0300136&rft.pages=e0300136-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0300136&rft_dat=%3Cgale_plos_%3EA798044806%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3069264057&rft_id=info:pmid/38885236&rft_galeid=A798044806&rft_doaj_id=oai_doaj_org_article_3b915df406634334990e58b6be70d1ff&rfr_iscdi=true |