Small RNA SmsR1 modulates acidogenicity and cariogenic virulence by affecting protein acetylation in Streptococcus mutans

Post-transcriptional regulation by small RNAs and post-translational modifications (PTM) such as lysine acetylation play fundamental roles in physiological circuits, offering rapid responses to environmental signals with low energy consumption. Yet, the interplay between these regulatory systems rem...

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Veröffentlicht in:	PLoS pathogens 2024-04, Vol.20 (4), p.e1012147-e1012147
Hauptverfasser:	Li, Jing, Ma, Qizhao, Huang, Jun, Liu, Yaqi, Zhou, Jing, Yu, Shuxing, Zhang, Qiong, Lin, Yongwang, Wang, Lingyun, Zou, Jing, Li, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Acetylation Analysis Animals Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Biofilms Biology and Life Sciences Care and treatment Complications and side effects Dehydrogenases Dental Caries - metabolism Dental Caries - microbiology Energy consumption Environmental stress Gene expression Gene Expression Regulation, Bacterial Gene regulation Humans Lysine Medicine and Health Sciences Messenger RNA Metabolism Mice Peptides Physical Sciences Physiology Post-transcription Post-translation Post-translational modification Protein Processing, Post-Translational Proteins Proteomics Research and Analysis Methods Ribonucleic acid RNA RNA, Bacterial - genetics RNA, Bacterial - metabolism RNA, Small Untranslated - genetics RNA, Small Untranslated - metabolism Streptococcal infections Streptococcus mutans Streptococcus mutans - genetics Streptococcus mutans - metabolism Streptococcus mutans - pathogenicity Transcription factors Transcriptomes Translation Variance analysis Virulence Virulence (Microbiology)
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