Aedes aegypti CCEae3A carboxylase expression confers carbamate, organophosphate and limited pyrethroid resistance in a model transgenic mosquito

Insecticide resistance is a serious threat to our ability to control mosquito vectors which transmit pathogens including malaria parasites and arboviruses. Understanding the underlying mechanisms is an essential first step in tackling the challenges presented by resistance. This study aimed to funct...

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Veröffentlicht in:	PLoS neglected tropical diseases 2024-02, Vol.18 (2), p.e0011595
Hauptverfasser:	Poulton, Beth C, Colman, Fraser, Anthousi, Amalia, Sattelle, David B, Lycett, Gareth J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adulticides Aedes - genetics Aedes aegypti Animals Animals, Genetically Modified Anopheles gambiae Aquatic insects Candidates Carbamate pesticides Carbamates Carbamates (tradename) Carboxylesterase Culicidae Cypermethrin Cytochrome Enzymes Fenitrothion Fenthion Genomes Human diseases Insecticide resistance Insecticides Insecticides - pharmacology Larvae Malaria Malathion Metabolism Mosquitoes Organophosphates Organophosphates - pharmacology Organothiophosphorus Compounds Parasites Pest control Pesticide resistance Pesticides Pyrethrins Pyrethroids Resistance mechanisms Temefos - pharmacology Toxicity Vector-borne diseases Vectors
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