Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export

Hepatitis B virus (HBV) chronically infects 296 million people worldwide, posing a major global health threat. Export of HBV RNAs from the nucleus to the cytoplasm is indispensable for viral protein translation and genome replication, however the mechanisms regulating this critical process remain la...

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Veröffentlicht in:	PLoS pathogens 2024-02, Vol.20 (2), p.e1011999-e1011999
Hauptverfasser:	Zheng, Yingcheng, Wang, Mengfei, Yin, Jiatong, Duan, Yurong, Wu, Chuanjian, Xu, Zaichao, Bu, Yanan, Wang, Jingjing, Chen, Quan, Zhu, Guoguo, Zhao, Kaitao, Zhang, Lu, Hua, Rong, Xu, Yanping, Hu, Xiyu, Cheng, Xiaoming, Xia, Yuchen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Biology and life sciences Core protein Cytoplasm Genomes Global health Health risks Heparan sulfate Hepatitis Hepatitis B Infections Medicine and health sciences Nuclear transport Plasmids Post-transcription Proteins Proteomics Public health Replication Research and Analysis Methods Ribonucleic acid RNA RNA transport Therapeutic targets Viruses
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