Evolution of HIV-1 envelope towards reduced neutralization sensitivity, as demonstrated by contemporary HIV-1 subtype B from the United States

Subtype B HIV-1 has been the primary driver of the HIV-1 epidemic in the United States (U.S.) for over forty years and is also a prominent subtype in the Americas, Europe, Australia, the Middle East and North Africa. In this study, the neutralization profiles of contemporary subtype B Envs from the...

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Veröffentlicht in:	PLoS pathogens 2023-12, Vol.19 (12), p.e1011780-e1011780
Hauptverfasser:	Wieczorek, Lindsay, Sanders-Buell, Eric, Zemil, Michelle, Lewitus, Eric, Kavusak, Erin, Heller, Jonah, Molnar, Sebastian, Rao, Mekhala, Smith, Gabriel, Bose, Meera, Nguyen, Amy, Dhungana, Adwitiya, Okada, Katherine, Parisi, Kelly, Silas, Daniel, Slike, Bonnie, Ganesan, Anuradha, Okulicz, Jason, Lalani, Tahaniyat, Agan, Brian K, Crowell, Trevor A, Darden, Janice, Rolland, Morgane, Vasan, Sandhya, Ake, Julie, Krebs, Shelly J, Peel, Sheila, Tovanabutra, Sodsai, Polonis, Victoria R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Antibodies Antibodies, Neutralizing Antigenicity Antiviral agents Binding sites Biological products Biology and Life Sciences Disease prevention Dosage and administration Entropy env Gene Products, Human Immunodeficiency Virus - genetics Epidemics Germany HIV HIV (Viruses) HIV Antibodies HIV infection HIV Infections HIV Seropositivity HIV-1 - genetics Human immunodeficiency virus Humans Infections Medicine and Health Sciences Military personnel Neutralization Neutralization Tests Northern Africa Pandemics Phylogenetics Physical Sciences Prevention Research and Analysis Methods Risk factors Testing United States - epidemiology Vaccines Viral antibodies
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