Direct and biologically significant interactions of human herpesvirus 8 interferon regulatory factor 1 with STAT3 and Janus kinase TYK2

Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that target cellular IRFs and/or other innate-immune and stress signaling regulators and suppress the cellular response to viral infection and replication. For vIRF-1, cellular protein targets include IRFs, p53, p53...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2023-11, Vol.19 (11), p.e1011806-e1011806
Hauptverfasser:	Yang, Zunlin, Xiang, Qiwang, Nicholas, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Analysis Antiviral agents Biological response modifiers Biology and Life Sciences Care and treatment Cytokines Deletion Diagnosis Dosage and administration Health aspects Herpes viruses Herpesvirus 8, Human - physiology Host-Pathogen Interactions Humans Infection Infections Interferon Interferon regulatory factor Interferon regulatory factor 1 Interferon Regulatory Factor-1 - metabolism Janus kinase Janus Kinases - metabolism Kinases Mutants Mutual fund industry p53 Protein Phosphatases Plasmids Proteins Regulation Replication Research and Analysis Methods Stat3 protein STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism Tumor Suppressor Protein p53 - metabolism TYK2 Kinase - genetics TYK2 Kinase - metabolism Tyk2 protein Virus diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!