Succinate utilisation by Salmonella is inhibited by multiple regulatory systems

Succinate is a potent immune signalling molecule that is present in the mammalian gut and within macrophages. Both of these infection niches are colonised by the pathogenic bacterium Salmonella enterica serovar Typhimurium during infection. Succinate is a C4-dicarboyxlate that can serve as a source...

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Veröffentlicht in:PLoS genetics 2024-03, Vol.20 (3), p.e1011142-e1011142
Hauptverfasser: Wenner, Nicolas, Zhu, Xiaojun, Rowe, Will P M, Händler, Kristian, Hinton, Jay C D
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Sprache:eng
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