Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis

In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted that, when the effects of homozygosity for recessive mutations are studied in n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS computational biology 2024-02, Vol.20 (2), p.e1011868-e1011868
Hauptverfasser:	Baer, Lachlan, Barthelson, Karissa, Postlethwait, John H, Adelson, David L, Pederson, Stephen M, Lardelli, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological evolution Chromosomes Danio rerio Datasets Gene expression Gene Expression Profiling Gene mapping Gene sequencing Genes Genotype Genotypes Heterozygotes Homeostasis Homozygosity Investigations Karyotypes Linkage disequilibrium Mutants Mutation Phenotypes Quantitative trait loci Quantitative Trait Loci - genetics Representations Ribonucleic acid RNA Transcriptome - genetics Transcriptomes Zebrafish Zebrafish - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!