Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway

Photoreceptor cells in the vertebrate retina have a highly compartmentalized morphology for efficient phototransduction and vision. Rhodopsin, the visual pigment in rod photoreceptors, is densely packaged into the rod outer segment sensory cilium and continuously renewed through essential synthesis...

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Veröffentlicht in:	PLoS biology 2024-01, Vol.22 (1), p.e3002467-e3002467
Hauptverfasser:	Haggerty, Kristen N, Eshelman, Shannon C, Sexton, Lauren A, Frimpong, Emmanuel, Rogers, Leah M, Agosto, Melina A, Robichaux, Michael A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biology and Life Sciences Cell Membrane Cell membranes Cytology Fluorescence microscopy Homeostasis Labeling Light Signal Transduction Localization Mammals Medicine and Health Sciences Membranes Mice Microscopy Microscopy, Fluorescence Monoclonal antibodies Mutation Photopigments Photoreception Photoreceptors Phototransduction Plasma Proteins Research and Analysis Methods Retina Retinal Rod Photoreceptor Cells Rhodopsin Rod outer segment membranes Segments Social Sciences Vertebrates Visual pigments
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