Fibroblast-induced mammary epithelial branching depends on fibroblast contractility

Epithelial branching morphogenesis is an essential process in living organisms, through which organ-specific epithelial shapes are created. Interactions between epithelial cells and their stromal microenvironment instruct branching morphogenesis but remain incompletely understood. Here, we employed...

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Veröffentlicht in:	PLoS biology 2024-01, Vol.22 (1), p.e3002093-e3002093
Hauptverfasser:	Sumbal, Jakub, Fre, Silvia, Sumbalova Koledova, Zuzana
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and Life Sciences Cell culture Epithelial cells Epithelium Experiments Fibroblasts Growth factors Kinases Mammary gland Mammary glands Medicine and Health Sciences Microenvironments Morphogenesis Muscle contraction Myosin Organoids Pattern formation Puberty Research and Analysis Methods Spheroids Statistical analysis Yes-associated protein
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