NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli

Trichomonas vaginalis is a human protozoan parasite that causes trichomoniasis, a prevalent sexually transmitted infection. Trichomoniasis is accompanied by a shift to a dysbiotic vaginal microbiome that is depleted of lactobacilli. Studies on co-cultures have shown that vaginal bacteria in eubiosis...

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Veröffentlicht in:	PLoS pathogens 2023-08, Vol.19 (8), p.e1011563-e1011563
Hauptverfasser:	Barnett, Michael J, Pinheiro, Jully, Keown, Jeremy R, Biboy, Jacob, Gray, Joe, Lucinescu, Ioana-Wilhelmina, Vollmer, Waldemar, Hirt, Robert P, Simoes-Barbosa, Augusto, Goldstone, David C
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaerobes Analysis Bacteria Biology and Life Sciences Composition Computer and Information Sciences Condoms Control Cysts Dysbacteriosis Enzymes Genes Genomes Gram-positive bacteria Health aspects Hydrolases Identification and classification Lactobacilli Medicine and Health Sciences Microbiomes Microbiota Microbiota (Symbiotic organisms) Mucosa Parasites Parasitic diseases Pathogenesis Peptides Peptidoglycans Phylogenetics Population control Prevention Proteins Protozoa Sexually transmitted diseases STD Trichomonas vaginalis Trichomoniasis Vagina Womens health
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