Enhanced Recovery After Surgery (ERAS) protocols following emergency intra-abdominal surgery: A systematic review and meta-analysis protocol
Objective The aim of this systematic review and meta-analysis is to evaluate whether the implementation of Enhanced Recovery After Surgery (ERAS) protocols for adult patients undergoing emergency intra-abdominal surgery decreases postoperative length of stay, postoperative morbidity, and mortality c...
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| Veröffentlicht in: | PloS one 2023-09, Vol.18 (9), p.e0291140 |
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| creator | McKechnie, Tyler Parpia, Sameer Bhandari, Mohit Dionne, Joanna C Eskicioglu, Cagla |
| description | Objective The aim of this systematic review and meta-analysis is to evaluate whether the implementation of Enhanced Recovery After Surgery (ERAS) protocols for adult patients undergoing emergency intra-abdominal surgery decreases postoperative length of stay, postoperative morbidity, and mortality compared to conventional perioperative care. Methods A systematic review and meta-analysis will be performed and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It has been registered on the International Prospective Register for Systematic Reviews (PROSPERO; CRD42023391709). A comprehensive, electronic search strategy will be used to identify studies published and indexed in MEDLINE, EMBASE, Web of Science, CENTRAL, and Pubmed databases since their inception. Trial registries and references of included studies and pertinent previous systematic reviews will also be searched. Studies will be included if they are randomized controlled trials or cohort studies evaluating adult patients undergoing emergency intra-abdominal surgery and comparing ERAS or modified ERAS protocols to conventional perioperative care and report one of the following outcomes: postoperative length of stay, overall 30-day morbidity, 30-day mortality, 30-day infectious morbidity, prolonged postoperative ileus, return of bowel function, and 30-day readmissions. A meta-analysis will be performed using a random effects model for all comparative data using Cochrane Review Manager 5.3 (London, United Kingdom). Discussion ERAS protocols have become standard of care for patients undergoing elective surgery. Their use in the setting of emergency surgery is far less common. The aim of this systematic review and meta-analysis is to assess whether there are benefits in patient important outcomes with the implementation of ERAS protocols for patients undergoing emergency intra-abdominal surgery. Ultimately, we hope to promote their use and further large randomized controlled trials evaluating emergency surgery ERAS programs. Prospero registration number CRD42023391709. |
| doi_str_mv | 10.1371/journal.pone.0291140 |
| format | Article |
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Methods A systematic review and meta-analysis will be performed and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It has been registered on the International Prospective Register for Systematic Reviews (PROSPERO; CRD42023391709). A comprehensive, electronic search strategy will be used to identify studies published and indexed in MEDLINE, EMBASE, Web of Science, CENTRAL, and Pubmed databases since their inception. Trial registries and references of included studies and pertinent previous systematic reviews will also be searched. Studies will be included if they are randomized controlled trials or cohort studies evaluating adult patients undergoing emergency intra-abdominal surgery and comparing ERAS or modified ERAS protocols to conventional perioperative care and report one of the following outcomes: postoperative length of stay, overall 30-day morbidity, 30-day mortality, 30-day infectious morbidity, prolonged postoperative ileus, return of bowel function, and 30-day readmissions. A meta-analysis will be performed using a random effects model for all comparative data using Cochrane Review Manager 5.3 (London, United Kingdom). Discussion ERAS protocols have become standard of care for patients undergoing elective surgery. Their use in the setting of emergency surgery is far less common. The aim of this systematic review and meta-analysis is to assess whether there are benefits in patient important outcomes with the implementation of ERAS protocols for patients undergoing emergency intra-abdominal surgery. Ultimately, we hope to promote their use and further large randomized controlled trials evaluating emergency surgery ERAS programs. Prospero registration number CRD42023391709.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0291140</identifier><identifier>PMID: 37682876</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Abdomen ; Abdominal surgery ; Analysis ; Canada ; Clinical trials ; Cohort analysis ; Elective surgery ; Evaluation ; Gastrointestinal surgery ; Health aspects ; Infections ; Intraabdominal surgery ; Laparotomy ; Length of stay ; Medical research ; Medicine and Health Sciences ; Medicine, Experimental ; Meta-analysis ; Methods ; Morbidity ; Mortality ; Patient outcomes ; Patients ; Perioperative care ; Physical Sciences ; Postoperative period ; Recovery ; Recovery (Medical) ; Research and Analysis Methods ; Study Protocol ; Surgery ; Systematic review</subject><ispartof>PloS one, 2023-09, Vol.18 (9), p.e0291140</ispartof><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 McKechnie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2023 McKechnie et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>2023 McKechnie et al 2023 McKechnie et al</rights><rights>2023 McKechnie et al. 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Methods A systematic review and meta-analysis will be performed and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It has been registered on the International Prospective Register for Systematic Reviews (PROSPERO; CRD42023391709). A comprehensive, electronic search strategy will be used to identify studies published and indexed in MEDLINE, EMBASE, Web of Science, CENTRAL, and Pubmed databases since their inception. Trial registries and references of included studies and pertinent previous systematic reviews will also be searched. 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Ultimately, we hope to promote their use and further large randomized controlled trials evaluating emergency surgery ERAS programs. 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titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McKechnie, Tyler</au><au>Parpia, Sameer</au><au>Bhandari, Mohit</au><au>Dionne, Joanna C</au><au>Eskicioglu, Cagla</au><au>Bennett, Sean</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enhanced Recovery After Surgery (ERAS) protocols following emergency intra-abdominal surgery: A systematic review and meta-analysis protocol</atitle><jtitle>PloS one</jtitle><date>2023-09-08</date><risdate>2023</risdate><volume>18</volume><issue>9</issue><spage>e0291140</spage><pages>e0291140-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Objective The aim of this systematic review and meta-analysis is to evaluate whether the implementation of Enhanced Recovery After Surgery (ERAS) protocols for adult patients undergoing emergency intra-abdominal surgery decreases postoperative length of stay, postoperative morbidity, and mortality compared to conventional perioperative care. Methods A systematic review and meta-analysis will be performed and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It has been registered on the International Prospective Register for Systematic Reviews (PROSPERO; CRD42023391709). A comprehensive, electronic search strategy will be used to identify studies published and indexed in MEDLINE, EMBASE, Web of Science, CENTRAL, and Pubmed databases since their inception. Trial registries and references of included studies and pertinent previous systematic reviews will also be searched. Studies will be included if they are randomized controlled trials or cohort studies evaluating adult patients undergoing emergency intra-abdominal surgery and comparing ERAS or modified ERAS protocols to conventional perioperative care and report one of the following outcomes: postoperative length of stay, overall 30-day morbidity, 30-day mortality, 30-day infectious morbidity, prolonged postoperative ileus, return of bowel function, and 30-day readmissions. A meta-analysis will be performed using a random effects model for all comparative data using Cochrane Review Manager 5.3 (London, United Kingdom). Discussion ERAS protocols have become standard of care for patients undergoing elective surgery. Their use in the setting of emergency surgery is far less common. The aim of this systematic review and meta-analysis is to assess whether there are benefits in patient important outcomes with the implementation of ERAS protocols for patients undergoing emergency intra-abdominal surgery. Ultimately, we hope to promote their use and further large randomized controlled trials evaluating emergency surgery ERAS programs. Prospero registration number CRD42023391709.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>37682876</pmid><doi>10.1371/journal.pone.0291140</doi><orcidid>https://orcid.org/0000-0002-7668-4096</orcidid><orcidid>https://orcid.org/0000-0002-9407-5622</orcidid><orcidid>https://orcid.org/0000-0003-3920-066X</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Abdominal surgery Analysis Canada Clinical trials Cohort analysis Elective surgery Evaluation Gastrointestinal surgery Health aspects Infections Intraabdominal surgery Laparotomy Length of stay Medical research Medicine and Health Sciences Medicine, Experimental Meta-analysis Methods Morbidity Mortality Patient outcomes Patients Perioperative care Physical Sciences Postoperative period Recovery Recovery (Medical) Research and Analysis Methods Study Protocol Surgery Systematic review |
| title | Enhanced Recovery After Surgery (ERAS) protocols following emergency intra-abdominal surgery: A systematic review and meta-analysis protocol |
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