Knockout of CLTC gene reduces but not completely block SFTSV infection

Clathrin is a key protein for viruses to enter host cells. Previous studies often use clathrin inhibitors or gene knockdown technology to partially inhibit the function of clathrin, but whether SFTSV can infect host cells without clathrin expression remains unclear. In this research, a clathrin heav...

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Veröffentlicht in:	PloS one 2023-08, Vol.18 (8), p.e0285673-e0285673
Hauptverfasser:	Liu, Tiezhu, Li, Jiajia, Wang, Xueqi, Huang, Tao, Wu, Wei, Li, Aqian, Li, Chuan, Huang, Xiaoxia, Wang, Qin, Li, Dexin, Wang, Shiwen, Liang, Mifang
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and Life Sciences Care and treatment Cell growth Clathrin Cloning CRISPR Diagnosis DNA sequencing Efficiency Endocytosis Ethylenediaminetetraacetic acid Evaluation Genes Health aspects Immunofluorescence Infection Infections Inhibitors Lipids Medical research Medicine, Experimental Nucleotide sequencing Plasmids Polyclonal antibodies Proteins Quantum dots Research and Analysis Methods Technology Thrombocytopenia Viruses
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