Attenuation hotspots in neurotropic human astroviruses

During the last decade, the detection of neurotropic astroviruses has increased dramatically. The MLB genogroup of astroviruses represents a genetically distinct group of zoonotic astroviruses associated with gastroenteritis and severe neurological complications in young children, the immunocompromi...

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Veröffentlicht in:	PLoS biology 2023-07, Vol.21 (7), p.e3001815
Hauptverfasser:	Ali, Hashim, Lulla, Aleksei, Nicholson, Alex S, Hankinson, Jacqueline, Wignall-Fleming, Elizabeth B, O'Connor, Rhian L, Vu, Diem-Lan, Graham, Stephen C, Deane, Janet E, Guix, Susana, Lulla, Valeria
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Astroviridae Infections - diagnosis Astroviridae Infections - veterinary Attenuation Biology and life sciences Capsid Capsid Proteins - genetics Cell culture Cell lines Child Child, Preschool Coding Complications Evolution Gastroenteritis Genetics Genomes Health aspects Humans Infections Livestock Mamastrovirus - genetics Medicine and Health Sciences Methods and Resources Neurological complications Neurotrophic functions Neurotropism Pathogenesis Phylogeny Proteins RNA polymerase RNA viruses Transcription Vaccines Viruses
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