Multiple pals gene modules control a balance between immunity and development in Caenorhabditis elegans

The immune system continually battles against pathogen-induced pressures, which often leads to the evolutionary expansion of immune gene families in a species-specific manner. For example, the pals gene family expanded to 39 members in the Caenorhabditis elegans genome, in comparison to a single mam...

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Veröffentlicht in:	PLoS pathogens 2023-07, Vol.19 (7), p.e1011120
Hauptverfasser:	Lažetić, Vladimir, Blanchard, Michael J, Bui, Theresa, Troemel, Emily R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Evolution Biology and Life Sciences Caenorhabditis elegans Caenorhabditis elegans - metabolism Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Computer and Information Sciences Engineering and Technology Epithelial cells Epithelium Gene expression Gene families Gene Regulatory Networks Genes Genetic aspects Genomes Growth Host-Pathogen Interactions - genetics Hypotheses Immune response Immune system Immunity Immunity, Innate - genetics Infections Intracellular Mammals Medicine and Health Sciences Microsporidia Modules Mutation Nematodes Parasitological research Pathogens Physiological aspects Proteins Research and Analysis Methods Viruses
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