Diabetes diminishes muscle precursor cell-mediated microvascular angiogenesis

The skeletal muscles of Type II diabetic (T2D) patients can be characterized by a reduced vessel density, corresponding to deficiencies in microvascular angiogenesis. Interestingly, T2D also inhibits the function of many myogenic cells resident within skeletal muscle, including satellite cells, whic...

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Veröffentlicht in:	PloS one 2023-08, Vol.18 (8), p.e0289477-e0289477
Hauptverfasser:	Acosta, Francisca M, Pacelli, Settimio, Rathbone, Christopher R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Angiogenesis Animal welfare Biology and Life Sciences Care and treatment Cells (biology) Computer software industry Diabetes Diabetes mellitus Diagnosis Disease Evaluation Exosomes Gene expression Genetic aspects Glucose Growth factors Homeostasis Insulin Interleukin 10 Interleukin 4 Interleukin 6 IP-10 protein Laboratory animals Leptin Medicine and Health Sciences MicroRNAs Microvasculature Monocyte chemoattractant protein 1 Muscles Musculoskeletal system Myoblasts Neovascularization Phosphates Physical Sciences Precursors Proteins Satellite cells Secretome Skeletal muscle Stem cells Tissue engineering Type 2 diabetes Vascular endothelial growth factor
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