Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity
Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A q...
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| creator | Shah, Shahid Abbas, Ghulam Aslam, Ayesha Randhawa, Fawad Ahmad Khan, Faiz Ullah Khurram, Haris Chand, Usman Rashid Butt, Muhammad Hammad Mallhi, Tauqeer Hussain Khan, Yusra Habib |
| description | Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant (p = |
| doi_str_mv | 10.1371/journal.pone.0289502 |
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This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant (p = <0.001) HRQoL VAS score55.1 (±23.2) of patients with the obesity. HRQoL VAS scores of patients with obesity were found to be higher when compared to patients with both T2D 49.8 (±15.4) and HTN 48.2 (±21). Diagnosis of one, two and three diseases showed significant results in VAS with all variables including gender (p = 0.004), educational level (p = <0.001), marital status (p<0.001), residence (p = <0.001), financial situation (p = <0.001) and monthly income (p = <0.001). The most frequently observed extremely problematic dimension was anxiety/ depression (47%) and the self-care (10%) was the least affected. Patient HRQoL is decreased by T2D, HTN, and obesity. The impact of these diseases coexisting is more detrimental to HRQoL.]]></description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0289502</identifier><identifier>PMID: 37540689</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Biology and Life Sciences ; Care and treatment ; Chi-square test ; Chronic illnesses ; Comorbidity ; Consent ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diagnosis ; Health aspects ; Hypertension ; Measuring instruments ; Medicine and Health Sciences ; Mortality ; Obesity ; Population studies ; Quality assessment ; Quality of life ; Quality standards ; Questionnaires ; Random sampling ; Regression models ; Research and Analysis Methods ; Sampling techniques ; Social Sciences ; Sociodemographics ; Statistical analysis ; Statistical sampling ; Type 2 diabetes</subject><ispartof>PloS one, 2023-08, Vol.18 (8), p.e0289502-e0289502</ispartof><rights>Copyright: © 2023 Shah et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Shah et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Shah et al 2023 Shah et al</rights><rights>2023 Shah et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c664t-c9aab40513de5210f3393b7dd717d0a652409f479917237e9ae8d8e30ef94e423</citedby><cites>FETCH-LOGICAL-c664t-c9aab40513de5210f3393b7dd717d0a652409f479917237e9ae8d8e30ef94e423</cites><orcidid>0000-0003-1814-4742 ; 0000-0003-4387-1351 ; 0000-0002-7396-8341</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403106/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403106/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,550,723,776,780,860,881,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37540689$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-511129$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Shah, Shahid</creatorcontrib><creatorcontrib>Abbas, Ghulam</creatorcontrib><creatorcontrib>Aslam, Ayesha</creatorcontrib><creatorcontrib>Randhawa, Fawad Ahmad</creatorcontrib><creatorcontrib>Khan, Faiz Ullah</creatorcontrib><creatorcontrib>Khurram, Haris</creatorcontrib><creatorcontrib>Chand, Usman Rashid</creatorcontrib><creatorcontrib>Butt, Muhammad Hammad</creatorcontrib><creatorcontrib>Mallhi, Tauqeer Hussain</creatorcontrib><creatorcontrib>Khan, Yusra Habib</creatorcontrib><title>Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity</title><title>PloS one</title><addtitle>PLoS One</addtitle><description><![CDATA[Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant (p = <0.001) HRQoL VAS score55.1 (±23.2) of patients with the obesity. HRQoL VAS scores of patients with obesity were found to be higher when compared to patients with both T2D 49.8 (±15.4) and HTN 48.2 (±21). Diagnosis of one, two and three diseases showed significant results in VAS with all variables including gender (p = 0.004), educational level (p = <0.001), marital status (p<0.001), residence (p = <0.001), financial situation (p = <0.001) and monthly income (p = <0.001). The most frequently observed extremely problematic dimension was anxiety/ depression (47%) and the self-care (10%) was the least affected. Patient HRQoL is decreased by T2D, HTN, and obesity. The impact of these diseases coexisting is more detrimental to HRQoL.]]></description><subject>Biology and Life Sciences</subject><subject>Care and treatment</subject><subject>Chi-square test</subject><subject>Chronic illnesses</subject><subject>Comorbidity</subject><subject>Consent</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diagnosis</subject><subject>Health aspects</subject><subject>Hypertension</subject><subject>Measuring instruments</subject><subject>Medicine and Health Sciences</subject><subject>Mortality</subject><subject>Obesity</subject><subject>Population studies</subject><subject>Quality assessment</subject><subject>Quality of life</subject><subject>Quality standards</subject><subject>Questionnaires</subject><subject>Random sampling</subject><subject>Regression models</subject><subject>Research and Analysis Methods</subject><subject>Sampling techniques</subject><subject>Social 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shah, Shahid</au><au>Abbas, Ghulam</au><au>Aslam, Ayesha</au><au>Randhawa, Fawad Ahmad</au><au>Khan, Faiz Ullah</au><au>Khurram, Haris</au><au>Chand, Usman Rashid</au><au>Butt, Muhammad Hammad</au><au>Mallhi, Tauqeer Hussain</au><au>Khan, Yusra Habib</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2023-08-04</date><risdate>2023</risdate><volume>18</volume><issue>8</issue><spage>e0289502</spage><epage>e0289502</epage><pages>e0289502-e0289502</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract><![CDATA[Obesity, hypertension (HTN) and type 2 diabetes (T2D) are among the multifactorial disorders that occur at higher prevalence in a population. This study aims to assess the health-related quality of life (HRQoL) of patients with obesity, HTN and T2D individually and in the form of multimorbidity. A questionnaire-based cross-sectional study was conducted among the patients in 15 private clinics of Punjab, Pakistan. A stratified random sampling technique was used to collect the data from patients with obesity, HTN and T2D or their comorbidity. A total of 1350 patients responded by completing the questionnaire. The HRQoL of these patients was assessed using the EQ-5D-5L questionnaire (a standardized instrument for measuring generic health status). Statistical analysis was performed using chi-square test, Mann-Whitney U test, and Kruskal-Wallis test. Multivariate linear regression model was used to model the visual analogue scale (VAS) score. In total, 15% of patients had combined obesity, HTN and T2D; 16.5% had HTN and T2D; 13.5% had obesity and HTN and 12.8% had obesity and T2D. Only 15.8% of patients had obesity, 14.3% had HTN, and 12% had T2D. Mann Whitney-U test gave the statistically significant (p = <0.001) HRQoL VAS score55.1 (±23.2) of patients with the obesity. HRQoL VAS scores of patients with obesity were found to be higher when compared to patients with both T2D 49.8 (±15.4) and HTN 48.2 (±21). Diagnosis of one, two and three diseases showed significant results in VAS with all variables including gender (p = 0.004), educational level (p = <0.001), marital status (p<0.001), residence (p = <0.001), financial situation (p = <0.001) and monthly income (p = <0.001). The most frequently observed extremely problematic dimension was anxiety/ depression (47%) and the self-care (10%) was the least affected. Patient HRQoL is decreased by T2D, HTN, and obesity. The impact of these diseases coexisting is more detrimental to HRQoL.]]></abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37540689</pmid><doi>10.1371/journal.pone.0289502</doi><tpages>e0289502</tpages><orcidid>https://orcid.org/0000-0003-1814-4742</orcidid><orcidid>https://orcid.org/0000-0003-4387-1351</orcidid><orcidid>https://orcid.org/0000-0002-7396-8341</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2023-08, Vol.18 (8), p.e0289502-e0289502 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2846186970 |
| source | Public Library of Science; Full-Text Journals in Chemistry (Open access); DOAJ Directory of Open Access Journals; PubMed Central; SWEPUB Freely available online; EZB Electronic Journals Library |
| subjects | Biology and Life Sciences Care and treatment Chi-square test Chronic illnesses Comorbidity Consent Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diagnosis Health aspects Hypertension Measuring instruments Medicine and Health Sciences Mortality Obesity Population studies Quality assessment Quality of life Quality standards Questionnaires Random sampling Regression models Research and Analysis Methods Sampling techniques Social Sciences Sociodemographics Statistical analysis Statistical sampling Type 2 diabetes |
| title | Assessment of health-related quality of life among patients with obesity, hypertension and type 2 diabetes mellitus and its relationship with multimorbidity |
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