A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke
Emerging data show an increased risk of ischemic stroke in patients with a new diagnosis of cancer. As the risk of stroke begins to increase 150 days before cancer is diagnosed, stroke may be the first clinical manifestation of undiagnosed cancer. About 6% of patients with cryptogenic ischemic strok...
Gespeichert in:
| Veröffentlicht in: | PloS one 2023-07, Vol.18 (7), p.e0289048-e0289048 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0289048 |
|---|---|
| container_issue | 7 |
| container_start_page | e0289048 |
| container_title | PloS one |
| container_volume | 18 |
| creator | Leentjens, Jenneke Chornenki, Nicholas L J Spiegelenberg, Janneke Ly, Valentina Dowlatshahi, Dariush Siegal, Deborah M |
| description | Emerging data show an increased risk of ischemic stroke in patients with a new diagnosis of cancer. As the risk of stroke begins to increase 150 days before cancer is diagnosed, stroke may be the first clinical manifestation of undiagnosed cancer. About 6% of patients with cryptogenic ischemic stroke (unknown etiology after diagnostic evaluations) are diagnosed with cancer within one year. However, the optimal cancer screening strategy in this population is not known. We aim to conduct a scoping review of screening strategies for occult cancer in individuals with ischemic stroke.
Electronic databases including MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCOhost) and Scopus will be systematically searched to identify articles that report on screening strategies for occult cancer in individuals with ischemic stroke. At least two investigators will independently perform two-stage study selection consisting of title/abstract screening and full-text review, followed by data extraction. Thereafter, a thematic analysis will be conducted to provide an overview of what diagnostic tests/strategies have been used, and their clinical utility in terms of positive and negative predictive value (when available).
We anticipate that the findings of this scoping review will identify strategies used to detect occult cancer in individuals with ischemic stroke and summarize their clinical utility (if reported). Addressing this knowledge gap will help guide the development of future clinical trials on occult cancer screening patients with ischemic stroke. |
| doi_str_mv | 10.1371/journal.pone.0289048 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2840628479</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A757995814</galeid><doaj_id>oai_doaj_org_article_6b0a9aa5b3a44905b92d91aa3022514a</doaj_id><sourcerecordid>A757995814</sourcerecordid><originalsourceid>FETCH-LOGICAL-c642t-b3f2bad543ae8ba01e3a54a28f9af25f4ab0fab11370dd2135e93432d018d4c73</originalsourceid><addsrcrecordid>eNqNk1tv0zAUxyMEYmPwDRBYQkLw0OJbLn5C1cSl0qRJ3F6tE9tJPVy7xE4H3x537aYG7QHFSiKf3_nb52-fonhO8Jywmry7CuPgwc03wZs5po3AvHlQnBLB6KyimD08-j8pnsR4hXHJmqp6XJywmtcNYeK0SAsUVdhY36PBbK25RpshpKCCQ8EjbaH3ISarUEwDJNNbE1EKSJtkVEJBqdEltAZnew9e7aLW56Ht1uoRXETXNq2QjWpl1nuV8NM8LR51OWaeHb5nxfePH76df55dXH5ani8uZqriNM1a1tEWdMkZmKYFTAyDkgNtOgEdLTsOLe6gJdkOrDUlrDSCcUY1Jo3mqmZnxcu97saFKA-GRUkbjqv8qkUmlntCB7iSm8GuYfgjA1h5MxGGXsKQy3dGVi0GAVC2DDgXuGwF1YIAMExpSThkrfeH1cZ2bbQyPlvmJqLTiLcr2YetJJhVpGQ4K7w5KAzh12hikuvsnHEOvAnjzcYJpgRjmtFX_6D3l3egesgVWN-FvLDaicpFXdZClA3hmZrfQ-VH784sX6_O5vlJwttJQmaS-Z16GGOUy69f_p-9_DFlXx-xKwMurWJwY7LBxynI96AaQoyD6e5cJljuuuPWDbnrDnnojpz24viE7pJu24H9BeaUC_M</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2840628479</pqid></control><display><type>article</type><title>A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Public Library of Science (PLoS)</source><creator>Leentjens, Jenneke ; Chornenki, Nicholas L J ; Spiegelenberg, Janneke ; Ly, Valentina ; Dowlatshahi, Dariush ; Siegal, Deborah M</creator><contributor>Ata, Fateen</contributor><creatorcontrib>Leentjens, Jenneke ; Chornenki, Nicholas L J ; Spiegelenberg, Janneke ; Ly, Valentina ; Dowlatshahi, Dariush ; Siegal, Deborah M ; Ata, Fateen</creatorcontrib><description>Emerging data show an increased risk of ischemic stroke in patients with a new diagnosis of cancer. As the risk of stroke begins to increase 150 days before cancer is diagnosed, stroke may be the first clinical manifestation of undiagnosed cancer. About 6% of patients with cryptogenic ischemic stroke (unknown etiology after diagnostic evaluations) are diagnosed with cancer within one year. However, the optimal cancer screening strategy in this population is not known. We aim to conduct a scoping review of screening strategies for occult cancer in individuals with ischemic stroke.
Electronic databases including MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCOhost) and Scopus will be systematically searched to identify articles that report on screening strategies for occult cancer in individuals with ischemic stroke. At least two investigators will independently perform two-stage study selection consisting of title/abstract screening and full-text review, followed by data extraction. Thereafter, a thematic analysis will be conducted to provide an overview of what diagnostic tests/strategies have been used, and their clinical utility in terms of positive and negative predictive value (when available).
We anticipate that the findings of this scoping review will identify strategies used to detect occult cancer in individuals with ischemic stroke and summarize their clinical utility (if reported). Addressing this knowledge gap will help guide the development of future clinical trials on occult cancer screening patients with ischemic stroke.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0289048</identifier><identifier>PMID: 37478139</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Biology and Life Sciences ; Canada ; Cancer ; Cancer screening ; Care and treatment ; Clinical trials ; Development and progression ; Diagnosis ; Diagnostic systems ; Etiology ; Evaluation ; Health risks ; Health sciences ; Internal medicine ; Ischemia ; Librarians ; Malignancy ; Medical diagnosis ; Medical screening ; Medicine ; Medicine and Health Sciences ; Mortality ; Registered Report Protocol ; Research and Analysis Methods ; Software ; Stroke ; Stroke (Disease) ; Systematic review ; Thromboembolism ; Writing ; Young adults</subject><ispartof>PloS one, 2023-07, Vol.18 (7), p.e0289048-e0289048</ispartof><rights>Copyright: © 2023 Leentjens et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</rights><rights>COPYRIGHT 2023 Public Library of Science</rights><rights>2023 Leentjens et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 Leentjens et al 2023 Leentjens et al</rights><rights>2023 Leentjens et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c642t-b3f2bad543ae8ba01e3a54a28f9af25f4ab0fab11370dd2135e93432d018d4c73</cites><orcidid>0000-0003-3356-3910</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361530/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361530/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,729,782,786,866,887,2106,2932,23875,27933,27934,53800,53802</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37478139$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Ata, Fateen</contributor><creatorcontrib>Leentjens, Jenneke</creatorcontrib><creatorcontrib>Chornenki, Nicholas L J</creatorcontrib><creatorcontrib>Spiegelenberg, Janneke</creatorcontrib><creatorcontrib>Ly, Valentina</creatorcontrib><creatorcontrib>Dowlatshahi, Dariush</creatorcontrib><creatorcontrib>Siegal, Deborah M</creatorcontrib><title>A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Emerging data show an increased risk of ischemic stroke in patients with a new diagnosis of cancer. As the risk of stroke begins to increase 150 days before cancer is diagnosed, stroke may be the first clinical manifestation of undiagnosed cancer. About 6% of patients with cryptogenic ischemic stroke (unknown etiology after diagnostic evaluations) are diagnosed with cancer within one year. However, the optimal cancer screening strategy in this population is not known. We aim to conduct a scoping review of screening strategies for occult cancer in individuals with ischemic stroke.
Electronic databases including MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCOhost) and Scopus will be systematically searched to identify articles that report on screening strategies for occult cancer in individuals with ischemic stroke. At least two investigators will independently perform two-stage study selection consisting of title/abstract screening and full-text review, followed by data extraction. Thereafter, a thematic analysis will be conducted to provide an overview of what diagnostic tests/strategies have been used, and their clinical utility in terms of positive and negative predictive value (when available).
We anticipate that the findings of this scoping review will identify strategies used to detect occult cancer in individuals with ischemic stroke and summarize their clinical utility (if reported). Addressing this knowledge gap will help guide the development of future clinical trials on occult cancer screening patients with ischemic stroke.</description><subject>Biology and Life Sciences</subject><subject>Canada</subject><subject>Cancer</subject><subject>Cancer screening</subject><subject>Care and treatment</subject><subject>Clinical trials</subject><subject>Development and progression</subject><subject>Diagnosis</subject><subject>Diagnostic systems</subject><subject>Etiology</subject><subject>Evaluation</subject><subject>Health risks</subject><subject>Health sciences</subject><subject>Internal medicine</subject><subject>Ischemia</subject><subject>Librarians</subject><subject>Malignancy</subject><subject>Medical diagnosis</subject><subject>Medical screening</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Mortality</subject><subject>Registered Report Protocol</subject><subject>Research and Analysis Methods</subject><subject>Software</subject><subject>Stroke</subject><subject>Stroke (Disease)</subject><subject>Systematic review</subject><subject>Thromboembolism</subject><subject>Writing</subject><subject>Young adults</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1tv0zAUxyMEYmPwDRBYQkLw0OJbLn5C1cSl0qRJ3F6tE9tJPVy7xE4H3x537aYG7QHFSiKf3_nb52-fonhO8Jywmry7CuPgwc03wZs5po3AvHlQnBLB6KyimD08-j8pnsR4hXHJmqp6XJywmtcNYeK0SAsUVdhY36PBbK25RpshpKCCQ8EjbaH3ISarUEwDJNNbE1EKSJtkVEJBqdEltAZnew9e7aLW56Ht1uoRXETXNq2QjWpl1nuV8NM8LR51OWaeHb5nxfePH76df55dXH5ani8uZqriNM1a1tEWdMkZmKYFTAyDkgNtOgEdLTsOLe6gJdkOrDUlrDSCcUY1Jo3mqmZnxcu97saFKA-GRUkbjqv8qkUmlntCB7iSm8GuYfgjA1h5MxGGXsKQy3dGVi0GAVC2DDgXuGwF1YIAMExpSThkrfeH1cZ2bbQyPlvmJqLTiLcr2YetJJhVpGQ4K7w5KAzh12hikuvsnHEOvAnjzcYJpgRjmtFX_6D3l3egesgVWN-FvLDaicpFXdZClA3hmZrfQ-VH784sX6_O5vlJwttJQmaS-Z16GGOUy69f_p-9_DFlXx-xKwMurWJwY7LBxynI96AaQoyD6e5cJljuuuPWDbnrDnnojpz24viE7pJu24H9BeaUC_M</recordid><startdate>20230721</startdate><enddate>20230721</enddate><creator>Leentjens, Jenneke</creator><creator>Chornenki, Nicholas L J</creator><creator>Spiegelenberg, Janneke</creator><creator>Ly, Valentina</creator><creator>Dowlatshahi, Dariush</creator><creator>Siegal, Deborah M</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-3356-3910</orcidid></search><sort><creationdate>20230721</creationdate><title>A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke</title><author>Leentjens, Jenneke ; Chornenki, Nicholas L J ; Spiegelenberg, Janneke ; Ly, Valentina ; Dowlatshahi, Dariush ; Siegal, Deborah M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c642t-b3f2bad543ae8ba01e3a54a28f9af25f4ab0fab11370dd2135e93432d018d4c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Biology and Life Sciences</topic><topic>Canada</topic><topic>Cancer</topic><topic>Cancer screening</topic><topic>Care and treatment</topic><topic>Clinical trials</topic><topic>Development and progression</topic><topic>Diagnosis</topic><topic>Diagnostic systems</topic><topic>Etiology</topic><topic>Evaluation</topic><topic>Health risks</topic><topic>Health sciences</topic><topic>Internal medicine</topic><topic>Ischemia</topic><topic>Librarians</topic><topic>Malignancy</topic><topic>Medical diagnosis</topic><topic>Medical screening</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Mortality</topic><topic>Registered Report Protocol</topic><topic>Research and Analysis Methods</topic><topic>Software</topic><topic>Stroke</topic><topic>Stroke (Disease)</topic><topic>Systematic review</topic><topic>Thromboembolism</topic><topic>Writing</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leentjens, Jenneke</creatorcontrib><creatorcontrib>Chornenki, Nicholas L J</creatorcontrib><creatorcontrib>Spiegelenberg, Janneke</creatorcontrib><creatorcontrib>Ly, Valentina</creatorcontrib><creatorcontrib>Dowlatshahi, Dariush</creatorcontrib><creatorcontrib>Siegal, Deborah M</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leentjens, Jenneke</au><au>Chornenki, Nicholas L J</au><au>Spiegelenberg, Janneke</au><au>Ly, Valentina</au><au>Dowlatshahi, Dariush</au><au>Siegal, Deborah M</au><au>Ata, Fateen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2023-07-21</date><risdate>2023</risdate><volume>18</volume><issue>7</issue><spage>e0289048</spage><epage>e0289048</epage><pages>e0289048-e0289048</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Emerging data show an increased risk of ischemic stroke in patients with a new diagnosis of cancer. As the risk of stroke begins to increase 150 days before cancer is diagnosed, stroke may be the first clinical manifestation of undiagnosed cancer. About 6% of patients with cryptogenic ischemic stroke (unknown etiology after diagnostic evaluations) are diagnosed with cancer within one year. However, the optimal cancer screening strategy in this population is not known. We aim to conduct a scoping review of screening strategies for occult cancer in individuals with ischemic stroke.
Electronic databases including MEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCOhost) and Scopus will be systematically searched to identify articles that report on screening strategies for occult cancer in individuals with ischemic stroke. At least two investigators will independently perform two-stage study selection consisting of title/abstract screening and full-text review, followed by data extraction. Thereafter, a thematic analysis will be conducted to provide an overview of what diagnostic tests/strategies have been used, and their clinical utility in terms of positive and negative predictive value (when available).
We anticipate that the findings of this scoping review will identify strategies used to detect occult cancer in individuals with ischemic stroke and summarize their clinical utility (if reported). Addressing this knowledge gap will help guide the development of future clinical trials on occult cancer screening patients with ischemic stroke.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>37478139</pmid><doi>10.1371/journal.pone.0289048</doi><tpages>e0289048</tpages><orcidid>https://orcid.org/0000-0003-3356-3910</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2023-07, Vol.18 (7), p.e0289048-e0289048 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2840628479 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Public Library of Science (PLoS) |
| subjects | Biology and Life Sciences Canada Cancer Cancer screening Care and treatment Clinical trials Development and progression Diagnosis Diagnostic systems Etiology Evaluation Health risks Health sciences Internal medicine Ischemia Librarians Malignancy Medical diagnosis Medical screening Medicine Medicine and Health Sciences Mortality Registered Report Protocol Research and Analysis Methods Software Stroke Stroke (Disease) Systematic review Thromboembolism Writing Young adults |
| title | A scoping review protocol on diagnostic strategies to detect occult malignancies in individuals with ischemic stroke |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-30T01%3A32%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20scoping%20review%20protocol%20on%20diagnostic%20strategies%20to%20detect%20occult%20malignancies%20in%20individuals%20with%20ischemic%20stroke&rft.jtitle=PloS%20one&rft.au=Leentjens,%20Jenneke&rft.date=2023-07-21&rft.volume=18&rft.issue=7&rft.spage=e0289048&rft.epage=e0289048&rft.pages=e0289048-e0289048&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0289048&rft_dat=%3Cgale_plos_%3EA757995814%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2840628479&rft_id=info:pmid/37478139&rft_galeid=A757995814&rft_doaj_id=oai_doaj_org_article_6b0a9aa5b3a44905b92d91aa3022514a&rfr_iscdi=true |