Community detection in empirical kinase networks identifies new potential members of signalling pathways

Phosphoproteomics allows one to measure the activity of kinases that drive the fluxes of signal transduction pathways involved in biological processes such as immune function, senescence and cell growth. However, deriving knowledge of signalling network circuitry from these data is challenging due t...

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Veröffentlicht in:PLoS computational biology 2023-06, Vol.19 (6), p.e1010459-e1010459
Hauptverfasser: Basanta, Celia De Los Angeles Colomina, Bazzi, Marya, Hijazi, Maruan, Bessant, Conrad, Cutillas, Pedro R
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Sprache:eng
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